Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Emerging trends and research hot spots in inborn error of immunity: A bibliometric perspective. [PDF]
Alblooshi H, Khan MJ, Almarzooqi F.
europepmc +1 more source
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Framing older adults' loneliness in Danish news media: between societal responsibility and individual burden. [PDF]
Ågren A, Cedersund E, Swane C.
europepmc +1 more source
Trends in Research on Plant Genetic Resources: Insects, Plant Diseases, and Genetic Diversity. [PDF]
Kim SH, Choi I.
europepmc +1 more source
High rates of spin bias in systematic reviews regarding anterior cervical discectomy and fusion <i>vs.</i> posterior cervical foraminotomy: a systematic review. [PDF]
Rusu D +8 more
europepmc +1 more source
Understanding the impact of social determinants of health in hematology: a scoping review of trends across journals and over time. [PDF]
Lu B +16 more
europepmc +1 more source
The relation between cerebral arteriovenous malformations and heart diseases in the pediatric population: a systematic review and meta-analysis. [PDF]
Ponchio V +8 more
europepmc +1 more source

