Results 201 to 210 of about 5,670,099 (298)

Depresión y factores asociados en personas viviendo con VIH/Sida en Quindío, Colombia, 2015

Revista Habanera de Ciencias Médicas
Deisy Viviana Cardona-Duque, Óscar Adolfo Medina-Pérez, Sandra Milena Herrera Castaño, Paula Andrea Orozco Gómez   +3 more
doaj  

Computational De Novo Design of Group II Introns Yields Highly Active Ribozymes. [PDF]

Chembiochem
Szokoli D, Nwosu NE, Glatt LM, Mutschler H.   +3 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Highly Active Antiretroviral Therapy (HAART) - "Sulfonyl", and anal cancer outcomes from patients living with HIV: a retrospective cohort. [PDF]

Infect Agent Cancer
Miranda RR, Rocha EA, de Almeida Robatto AA, Galhera DA, Victor CR, Imbrahim KY, Moniz CMV.   +6 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Highly Active Carbonic Anhydrase of the Thylakoid Lumen of Chlamydomonas reinhardtii. [PDF]

Plants (Basel)
Terentyev VV, Trubitsina LI, Shukshina AK, Trubitsin IV, Rudenko NN.   +4 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Defect-Engineered CoSe₂ Quantum Dots Exposing Highly Active (111) Facets with Lithiophilic-Sulfurophilic Functionality for High-Energy Lithium-Sulfur Batteries. [PDF]

Adv Sci (Weinh)
Li X, Yu J, Jin T, Li Y, Shi Y, Jiang Y, Liu X, Huang S, Uvdal K, Zhao B, Zhang J.   +10 more
europepmc   +1 more source