Results 291 to 300 of about 13,575,187 (324)
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Science, 2007
The observation that biological activity in eddies can be very high may help explain why measurements of ocean productivity have varied widely.
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The observation that biological activity in eddies can be very high may help explain why measurements of ocean productivity have varied widely.
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HIGHLY ACTIVE ANTICANCER CURCUMIN ANALOGUES
2007Curcumin, a compound in the human food supply, represents a near-perfect starting point for drug discovery. Consequently, a number of research groups have taken the natural product as a starting point to prepare and biologically evaluate a wide variety of curcumin analogues.
Cara A, Mosley +2 more
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Highly Active Myeloid Therapy for Cancer
ACS Nano, 2023Tumor-associated macrophages (TAM) interact with cancer and stromal cells and are integral to sustaining many cancer-promoting features. Therapeutic manipulation of TAM could therefore improve clinical outcomes and synergize with immunotherapy and other cancer therapies.
Ina R. Fredrich +5 more
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An Isolated Zinc-Cobalt Atomic Pair for Highly Active and Durable Oxygen Reduction.
Angewandte Chemie, 2019A competitive complexation strategy has been developed to construct a novel electrocatalyst with Zn-Co atomic pairs coordinated on N doped carbon support (Zn/CoN-C).
Ziyang Lu +14 more
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Journal of the American Chemical Society, 2019
Developing an active and stable metal single-atom catalyst (SAC) is challenging due to the high surface free energy of metal atoms. In this work, we report that tailoring of the 5d state of Pt1 single atoms on Co3O4 through strong electronic metal ...
Junjie Li +13 more
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Developing an active and stable metal single-atom catalyst (SAC) is challenging due to the high surface free energy of metal atoms. In this work, we report that tailoring of the 5d state of Pt1 single atoms on Co3O4 through strong electronic metal ...
Junjie Li +13 more
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Water Research, 2019
The global energy crisis and water pollution drive the researchers to develop highly effective and less energy intensive water purification technologies.
Zhengqing Cai +5 more
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The global energy crisis and water pollution drive the researchers to develop highly effective and less energy intensive water purification technologies.
Zhengqing Cai +5 more
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A highly active synthetic mammalian retrotransposon
Nature, 2004LINE-1 (L1) elements are retrotransposons that comprise large fractions of mammalian genomes. Transcription through L1 open reading frames is inefficient owing to an elongation defect, inhibiting the robust expression of L1 RNA and proteins, the substrate and enzyme(s) for retrotransposition.
Jeffrey S, Han, Jef D, Boeke
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Phosphorylation Organocatalysts Highly Active by Design
Organic Letters, 2020The activity of nucleophilic organocatalysts for alcohol/phenol phosphorylation was enhanced through attaching oligoether appendages to a benzyl substituent on imidazole- or aminopyridine-based active units, presumably because of stabilizing n-cation interactions of the ethereal oxygens with the positively charged aza-heterocycle in the catalytic ...
Amit Fallek +4 more
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Highly efficient catalase activity of metallocorroles
Chemical Communications, 2010The iron(iii) complex of a bipolar and amphiphilic corrole, which binds strongly to proteins and undergoes protein-mediated cellular uptake, catalyzes the decomposition of hydrogen peroxide faster (k(cat) = 6400 M(-1) s(-1)) and more efficiently (turnover frequency >120 s(-1)) than previously reported synthetic compounds with catalase-like activity.
Atif, Mahammed, Zeev, Gross
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Highly Sensitive Electrochemical Methyltransferase Activity Assay
Analytical Chemistry, 2014A simple and highly sensitive electrochemical DNA methyltransferase (MTase) activity assay is presented in this report. The assay employs the electrocatalytic oxidation of ascorbic acid (AA) by a threading intercalator (N,N'-bis(3-propylimidazole)-1,4,5,8-naphthalene diimide (PIND) functionalized with electrocatalytic redox Os(bpy)2Cl(+) moieties (PIND-
Deng, H., Yang, X., Yeo, S.P.X., Gao, Z.
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