Results 201 to 210 of about 1,023,504 (281)

A Comprehensive In Vitro Approach for Assessing the Physiological Degradation of Medical Implants: The Silkothane Arteriovenous Graft Case Study

open access: yesAdvanced NanoBiomed Research, EarlyView.
Evaluating the degradation of absorbable medical devices in vitro demands physiologically relevant conditions. This study presents a comprehensive framework applied to a three‐layered silk fibroin/polyurethane arteriovenous graft, employing human enzymes at physiological concentrations over 6 months. Multiparametric analyses of both graft structure and
Cristina Oldani   +5 more
wiley   +1 more source

Switching ATP‐Forming Phosphoryl‐Transfer Chemistry With a Restricted Set of Amino Acids

open access: yesAngewandte Chemie, EarlyView.
Constraints on amino acid composition relevant to prebiotic chemistry reshape enzyme chemistry by replacing the canonical mechanism within a conserved protein fold with a distinct ATP‐forming reaction, ADP disproportionation. Such constraints generate alternative catalytic solutions not observed in modern enzymes and point to chemically plausible early
Sota Yagi   +3 more
wiley   +2 more sources

Novel Interdigitated Electrode Conductometric Sensor for Rapid, Sensitive, and Selective Detection of cTnI Biomarkers in Saliva

open access: yesAdvanced NanoBiomed Research, EarlyView.
A miniaturized high resistivity silicon‐based interdigitated conductometric sensor detects cTnI at sub‐femtomolar levels with high selectivity. The device enables noninvasive testing using artificial and pooled human saliva in real‐time electrical readings. This portable biosensor offers a promising futuristic medical device providing new opportunities
Preethi Chidambaram   +8 more
wiley   +1 more source

An IscS Persulfide Donates the Sulfur for Ribosomal Protein uL16 Thioamidation

open access: yesAngewandte Chemie, EarlyView.
YcaO‐catalyzed thioamidation of the ribosomal subunit protein uL16 is widespread in Pseudomonadota bacteria. We identify the iron–sulfur cluster cysteine desulfurase IscS as the sulfur donor via an IscS persulfide and observe direct IscS–uL16 interactions.
Yanqing Xue   +2 more
wiley   +2 more sources

Dialkyl Ethers and Sacrificial Zinc: Oxide Synthons for Calcium tert‐Butoxide Formation

open access: yesAngewandte Chemie, EarlyView.
When treated with dialkyl ethers, [(BDI)Ca‐μ‐H‐Zn(t‐Bu)2(η6‐C7H8)] (BDI = HC{C(Me)NDipp}2 initiates a sequence of twofold ether dealkylation and oxide sequestration as tert‐butoxide in a process predicated on a combination of extreme basicity and a cooperative redox process administered by the dissimilar constituent metals. (Generative AI (ChatGPT) was
Kyle G. Pearce   +3 more
wiley   +2 more sources

Charles Lee Hill Headshot - Back

open access: yes
Charles Lee Hill at age 73 Coud. Of "The Good Times Brass Band," Houston, Texas Former Assoc.

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