Results 181 to 190 of about 1,257,208 (301)

Fn14 Controls the SIRT2‐Mediated Deacetylation of Slug to Inhibit the Metastasis of Epithelial Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
It is reported that Fn14 inhibited EOC metastasis by regulating Slug‐mediated EMT. Furthermore, Fn14 altered the subcellular localization of SIRT2 by interacting with SIRT2, leading to reduced SIRT2 shuttling into the nucleus and subsequently promoting the acetylated degradation of Slug.
Anyue Wu   +9 more
wiley   +1 more source

Biomedical Applications of Gadolinium‐Containing Biomaterials: Not Only MRI Contrast Agent

open access: yesAdvanced Science, EarlyView.
This paper summarizes the latest applications and potential mechanisms of the rare earth element gadolinium in biomedical fields, in addition to its traditional application as an MRI contrast agent, including osteogenesis, antimicrobial, antitumor, bioimaging, bioprobes, and so on.
Xingtong Pan   +9 more
wiley   +1 more source

Biomechanical features of a novel step-down-and-pivot task in football players with hip/groin pain. [PDF]

open access: yesR Soc Open Sci
Sritharan P   +10 more
europepmc   +1 more source

AI‐Driven Defecation Analysis by Smart Healthcare Toilet: Exploring Biometric Patterns and Eu‐Tenesmus

open access: yesAdvanced Science, EarlyView.
A healthcare toilet system is introduced to passively measure defecation behavior. Real‐time data on stool dropping duration, thickness, and a newly defined “eu‐tenesmus” interval show correlations with stool form and gender differences. Results from 45 defecation events reveal a promising method for comprehensive defecation analysis.
Zhiquan Song   +16 more
wiley   +1 more source

PIP5K1A Suppresses Ferroptosis and Induces Sorafenib Resistance by Stabilizing NRF2 in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Inducing ferroptosis is a promising strategy for combating tumor resistance. Upregulated PIP5K1A competes with NRF2 for KEAP1 binding, which decreases the ubiquitination degradation of NRF2 and promotes its nuclear translocation, thereby suppressing ferroptosis, and ultimately driving hepatocellular carcinoma (HCC) tumorigeneses and sorafenib ...
Mengzhou Guo   +9 more
wiley   +1 more source

Scalable and Integrated Photocatalytic Reactor Systems for Solar‐to‐Fuel Production: Photoredox and Photoreforming Processes

open access: yesAdvanced Energy Materials, EarlyView.
Solar fuels and other value‐added chemicals derived from light‐driven reactions are highly desirable. Although advanced photoactive materials have been reported, demonstrations of their feasibility in large‐scale production are needed. Hence, strategies and recent efforts in scaling up photocatalytic reactors and integrating them into comprehensive ...
Hoi Ying Chung   +5 more
wiley   +1 more source

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