Results 171 to 180 of about 373,886 (302)

Perioperative Management in Persons With Haemophilia on Rebalancing Therapies: A Narrative Review

Haemophilia, EarlyView.
ABSTRACT Introduction Perioperative management in haemophilia often requires on‐demand use of clotting factor concentrates (CFC) and/or bypassing agents. Rebalancing agents (fitusiran, concizumab, marstacimab) offer a novel approach to prophylaxis by modulating endogenous anticoagulant pathways to restore haemostatic balance.
Amanda M. Henderson, Roy Khalife, Kelsey Uminski   +2 more
wiley   +1 more source

Utility of the Clinical Frailty Scale, Charlson Comorbidity Index and ACS NSQIP Surgical Risk Calculator in major lower limb orthopaedic surgery

Internal Medicine Journal, EarlyView.
Abstract Background With major lower limb orthopaedic surgery performed in increasingly older and comorbid patients, accurate risk prediction is essential to guide perioperative management and shared decision‐making. Aims To compare the Clinical Frailty Scale (CFS), Charlson Comorbidity Index (CCI) and the American College of Surgeons National Surgical
Alexa Yao, Emily Schembri, Ejoy Zhang, Raphael Hau, Christopher Fong   +4 more
wiley   +1 more source

Trends in Dispensing of Opioids and Benzodiazepines Among Older Adults Admitted for an Acute Hip Fracture Between 2008 and 2024 in Ontario, Canada

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Introduction Opioids and benzodiazepines (BZDs) are commonly prescribed for managing pain, anxiety, and sleep‐related problems following a hip fracture. Both opioids and BZDs carry risks of persistent dependence, falls, and mortality with long‐term use. Despite these risks, Canada lacks standardized prescribing guidelines for older adults with
Anum Ali, Mina Tadrous, Chizaram Eje, Laleh Rashidian, Arrani Senthinathan, Cherry Chu, Kerry Kuluski, Sara J. T. Guilcher   +7 more
wiley   +1 more source

Aging‐related morphological changes in the obturator internus and levator ani

Journal of Anatomy, EarlyView.
A cross‐sectional MRI‐based morphometric analysis of 27 women aged 25–83 years revealed age‐associated morphological differences in the obturator internus and levator ani. Older age was associated with relative superior narrowing of the obturator internus, inferior displacement of its groove and medial eminence, a more vertical orientation of the ...
Satoru Muro, Junichi Tsuchiya, Takuya Ibara, Akimoto Nimura, Keiichi Akita   +4 more
wiley   +1 more source

Association Between Perceived Quality of Postoperative Pain Care and Patient‐Reported Outcomes After Total Knee or Total Hip Arthroplasty: A Cross‐Sectional Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim This study aimed to examine the relationship between perceived quality of postoperative pain care and patient‐reported pain‐related outcomes in patients undergoing total knee or total hip arthroplasty and to identify factors associated with higher perceived care quality. Design A descriptive, cross‐sectional study.
Serdar Sever, Dilan Temir, Elif Nazlı Çelen, Sümeyra Karaduman   +3 more
wiley   +1 more source

Associations Between Weight Loss Prior to Knee and Hip Arthroplasty and Peri‐ and Post‐Operative Outcomes: A Systematic Review and Meta‐Analysis

Obesity Reviews, EarlyView.
ABSTRACT Background In some of the existing literature, obesity is associated with increased complications in those who undergo lower limb arthroplasty. We conducted a systematic review and meta‐analysis to assess if pre‐arthroplasty weight loss mitigates increased post‐operative risks. Methods This systematic review and meta‐analysis was registered on
Moneet Gill, Tim Lindsay, Daniel Kevin Llanera, Tricia M.‐M. Tan, Alex Liddle, Chioma Izzi‐Engbeaya   +5 more
wiley   +1 more source

Treatment Trade‐Offs and Choices for Femoral Fractures: A Systematic Review and Meta‐Analysis

Orthopaedic Surgery, Volume 17, Issue 5, Page 1298-1313, May 2025.
This review examines the trade‐offs between surgical intervention and traction therapy for adult and elderly patients with femoral fractures and surgical contraindications, particularly in resource‐limited settings. While intramedullary nailing may offer better clinical outcomes, traction therapy is often preferred due to limited surgical resources ...
Jiarui Li, Zhu Guo, Tianrui Wang, Kunyue Xing, Wenzhuo Wang, Yaowei Liu, Jiyao Xing, Hongfei Xiang, Jingdong Wang, Bohua Chen, Dongming Xing, Xiaolin Wu   +11 more
wiley   +1 more source

Can Knee Arthroscopy Be Considered Entirely Safe for Patients Over 50 Years Old With no Risk of Osteonecrosis? Case Series and Literature Review on Post‐Artrhoscopy Osteonecrosis of the Knee (PAONK)

Orthopaedic Surgery, Volume 17, Issue 5, Page 1378-1388, May 2025.
Post‐arthroscopy osteonecrosis is a rare complication occurring in 0.82% of cases, primarily affecting patients over 50 with degenerative meniscal tears. Early detection through MRI and conservative treatment, including bisphosphonates and weight‐bearing avoidance, proved effective in most cases, while some required surgical intervention.
Panagiotis Ntagiopoulos, Georgios Kalinterakis, Pierrenzo Pozzi, Dimitris Fligkos, George Themistocleous, Sotirios Themistokleous, Triantafyllia Dimou, Riccardo Compagnoni, Paolo Ferrua, Pietro Simone Randelli   +9 more
wiley   +1 more source

Creating Perforations in the Sclerotic Region of the Proximal Tibia During Total Knee Arthroplasty to Enhance Prosthesis Stability

Orthopaedic Surgery, Volume 17, Issue 5, Page 1397-1405, May 2025.
Abnormal stress in the proximal tibia modifies the bone mineral density distribution pattern, and drilling in the sclerotic region during total knee arthroplasty is correlated with enhanced prosthesis stability. ABSTRACT Objective In patients with varus deformity of the knee, the redistribution of the subchondral bone mineral density (BMD) of the tibia
Chao Sun, Chunyan Wang, Jintang Li, Chengyan Liu, Zhilin Wei, Zhiguo Bi, Yeran Li, Shuqiang Li   +7 more
wiley   +1 more source

Customized Metal 3D Printed Total Wrist Prosthesis in the Treatment of Severely Destroyed Wrist: Design Rationale and Clinical Applications

Orthopaedic Surgery, Volume 17, Issue 5, Page 1536-1546, May 2025.
Four patients with severe wrist destruction from various causes were treated with customized 3D‐printed prostheses. In addition to the specific articular surface matching their original radiocarpal joint, two innovative proximal component designs were created to address different bone defects.
Qipei Wei, Chang Liu, Shanlin Chen, Min Liu   +3 more
wiley   +1 more source