Results 211 to 220 of about 40,941 (291)

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

open access: yesExperimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu   +4 more
wiley   +1 more source

Applying lessons from limb muscle disuse and ageing to better understand ventilator‐induced diaphragm dysfunction

open access: yesExperimental Physiology, EarlyView.
Abstract Mechanical ventilation (MV) is a life‐saving intervention applied to critically ill patients. A common consequence of MV is ventilator‐induced diaphragm dysfunction (VIDD), which is characterized by significant diaphragm atrophy and reduced contractile function. Older patients who receive MV are more likely to develop VIDD, have worse recovery,
P. H. C. Mesquita   +3 more
wiley   +1 more source

Osteochondral Allograft Transplantation of the Femoral Head via Surgical Hip Dislocation: Survivorship and Patient Reported Outcome Measures at Minimum 2-Year Follow-Up. [PDF]

open access: yesOrthop J Sports Med
Uppstrom TJ   +9 more
europepmc   +1 more source

Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle

open access: yesExperimental Physiology, EarlyView.
Abstract MicroRNAs (miRNAs) are key regulators of cellular processes, including mitochondrial function and energy metabolism. This study explores the regulation of miR‐494 in skeletal muscle and circulation, investigating its response to exercise training and an acute exercise bout, its association with metabolic disorders, and the effects of ...
Natália Pálešová   +10 more
wiley   +1 more source

Role of S1P‐ and Rho‐kinase signalling in age‐related myogenic tone deficiency in murine resistance arteries

open access: yesExperimental Physiology, EarlyView.
Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted   +11 more
wiley   +1 more source

Endoscopic Step‐up Approach for Walled‐off Necrosis After Acute Pancreatitis

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT This review outlines current interventional strategies for treating symptomatic walled‐off necrosis (WON) after necrotizing pancreatitis. Mortality from acute pancreatitis has improved, but late mortality, particularly from infected necrosis, remains a challenge. WON requires invasive treatment in cases of infection or symptoms.
Shuntaro Mukai   +13 more
wiley   +1 more source

Open‐Source Simulator of Imaging Near Metal at Arbitrary Magnetic Field Strengths

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 4, Page 2370-2383, April 2026.
ABSTRACT Purpose The increasing prevalence of orthopedic metallic implants necessitates optimization of MRI methods to monitor surrounding tissues and identify complications. The emergence of contemporary mid‐ and low‐field systems as promising platforms for imaging around metal requires development of new protocols optimized for these field strengths.
Kübra Keskin   +3 more
wiley   +1 more source

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