Results 11 to 20 of about 22,590 (246)

Differential genetic regulation of canine hip dysplasia and osteoarthritis. [PDF]

PLoS ONE, 2010
BackgroundCanine hip dysplasia (HD) is a common polygenic trait characterized by hip malformation that results in osteoarthritis (OA). The condition in dogs is very similar to developmental dysplasia of the human hip which also leads to OA.Methodology ...
Zhengkui Zhou, Xihui Sheng, Zhiwu Zhang, Keyan Zhao, Lan Zhu, Gang Guo, Steve G Friedenberg, Linda S Hunter, Wendy S Vandenberg-Foels, William E Hornbuckle, Ursula Krotscheck, Elizabeth Corey, Nancy S Moise, Nathan L Dykes, Junya Li, Shangzhong Xu, Lixin Du, Yachun Wang, Jody Sandler, Gregory M Acland, George Lust, Rory J Todhunter   +21 more
doaj   +3 more sources

Prevalence of lumbosacral transitional vertebrae and association with hip dysplasia in Rhodesian Ridgebacks in Germany. [PDF]

Vet Med (Praha)
Congenital anomalies affecting the spinal column are frequently observed in certain dog breeds. One such condition occurs at the junction between the lower back and the sacrum, where vertebrae exhibit mixed structural characteristics.
Slunsky SK, Slunsky P, Fort E, Brunnberg L.   +3 more
europepmc   +2 more sources

Genetic dissection of canine hip dysplasia phenotypes and osteoarthritis reveals three novel loci

BMC Genomics, 2019
Background Hip dysplasia and osteoarthritis continue to be prevalent problems in veterinary and human medicine. Canine hip dysplasia is particularly problematic as it massively affects several large-sized breeds and can cause a severe impairment of the ...
Lea Mikkola, Saila Holopainen, Tiina Pessa-Morikawa, Anu K. Lappalainen, Marjo K. Hytönen, Hannes Lohi, Antti Iivanainen   +6 more
doaj   +2 more sources

Genome-wide association study to identify canine hip dysplasia loci in dogs

Journal of Animal Science and Technology, 2020
Korean army dogs are raised for special purposes and have contributed much to society. However, several diseases occur in dogs. Canine hip dysplasia (CHD) is a musculoskeletal disorder that occurs frequently in ...
Ji Min Kang, Dongwon Seo, Soo Hyun Lee, Doo Ho Lee, Yeong Kuk Kim, Bong Hwan Choi, Seung Hwan Lee   +6 more
doaj   +2 more sources

An across-breed validation study of 46 genetic markers in canine hip dysplasia

BMC Genomics, 2021
Background Canine hip dysplasia (CHD) is a common disease, with a complex genetic background. Dogs with severe CHD sometimes also suffer from osteoarthritis (OA), an inflammatory, often painful and incurable condition.
Lea Mikkola, Kaisa Kyöstilä, Jonas Donner, Anu K. Lappalainen, Marjo K. Hytönen, Hannes Lohi, Antti Iivanainen   +6 more
doaj   +2 more sources

Genetic analyses of lumbosacral transitional vertebra and hip dysplasia in nine dog breeds in Norway. [PDF]

Acta Vet Scand
A lumbosacral transitional vertebra (LTV) is a congenital anomaly with reported prevalences ranging from 0 to 67% in different dog breeds, implying possible genetic differences.
Berg JA, Sævik BK, Trangerud C, Madsen P, Lingaas F.   +4 more
europepmc   +2 more sources

Early Diagnosis of Canine Hip Laxity: Correlation between Clinical Orthopedic Examinations and the FCI Scoring Method in a Closed Cohort of Rottweilers

Animals, 2021
Canine hip dysplasia is a multifactorial disorder characterized by hip laxity and osteoarthritis. The early diagnosis of hip laxity is an important topic in small animal orthopedics.
Britta Vidoni, Veronika Bauer, Barbara Bockstahler, Michaela Gumpenberger, Alexander Tichy, Masoud Aghapour   +5 more
doaj   +3 more sources

Genome-wide association studies for canine hip dysplasia in single and multiple populations – implications and potential novel risk loci

BMC Genomics, 2021
Background Association mapping studies of quantitative trait loci (QTL) for canine hip dysplasia (CHD) can contribute to the understanding of the genetic background of this common and debilitating disease and might contribute to its genetic improvement ...
Shizhi Wang, Erling Strandberg, Per Arvelius, Dylan N. Clements, Pamela Wiener, Juliane Friedrich   +5 more
doaj   +3 more sources

Automated Assessment of Pelvic Longitudinal Rotation Using Computer Vision in Canine Hip Dysplasia Screening. [PDF]

Vet Sci
Simple Summary Canine hip dysplasia is a painful condition common in large dog breeds, leading to joint instability and osteoarthritis. Accurate diagnosis is crucial for guiding breeding decisions to help reduce its prevalence.
Franco-Gonçalo P, Leite P, Alves-Pimenta S, Colaço B, Gonçalves L, Filipe V, McEvoy F, Ferreira M, Ginja M.   +8 more
europepmc   +2 more sources

Canine hip dysplasia is predictable by genotyping [PDF]

Osteoarthritis and Cartilage, 2011
To establish a predictive method using whole genome genotyping for early intervention in canine hip dysplasia (CHD) risk management, for the prevention of the progression of secondary osteoarthritis (OA), and for selective breeding.Two sets of dogs (six breeds) were genotyped with dense SNPs covering the entire canine genome.
Guo, Gang, Zhou, Zhengkui, Wang, Yachun, Zhao, Keyan, Zhu, Lan, Lust, George, Hunter, Linda, Friedenberg, Steven, Li, Junya, Zhang, Yuan, Harris, Stephen, Jones, Paul, Sandler, Jody, Krotscheck, Ursula, Todhunter, Rory, Zhang, Zhiwu   +15 more
openaire   +5 more sources