Results 81 to 90 of about 22,590 (246)

From Molecule to Meaning: Neuronopathic Biomarkers and Clinical Relevance in GM1

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT GM1 gangliosidosis is a rare, progressively neurodegenerative lysosomal storage disorder characterized by profound central nervous system involvement and substantial clinical heterogeneity. The development of reliable biomarkers is essential for tracking disease progression, stratifying patients, and advancing clinical trial readiness. Primary
Krista Casazza, Roberto Giugliani, Debra S. Regier, Jeanine Jarnes   +3 more
wiley   +1 more source

A systemic review of existing serological possibilities to diagnose canine osteoarthritis with a particular focus on extracellular matrix proteoglycans and protein [PDF]

, 2017
Extra-cellular matrix (ECM) components are important and their stabilization is significant in maintaining normal healthy joint environment. In osteoarthritis (OA), ECM components are altered and indicate disease progression. The joint ECM is composed
Fatima, A., Leo, B., Manchi, G., Naseer, 0., Raila, J., Shahid, M., Slunsky, P.   +6 more
core   +1 more source

Prevalence of canine hip dysplasia in 10 breeds in France, a retrospective study of the 1997-2017 radiographic screening period

PLoS ONE, 2020
Canine hip dysplasia (HD) is a complex developmental disease of the coxo-femoral joint and is one of the most common orthopedic conditions in dogs. Due to the genetic contribution, most of the programs fighting against HD recommend selective breeding ...
A. Baldinger, J. Genevois, P. Moissonnier, A. Barthélemy, C. Carozzo, E. Viguier, T. Cachon   +6 more
semanticscholar   +1 more source

Systematic review of surgical treatment for severe elbow osteoarthritis in dogs

Veterinary Surgery, Volume 55, Issue 1, Page 32-38, January 2026.
Abstract Objective To determine the evidence for the most effective surgical treatment for elbow osteoarthritis with the least harm in dogs. Study design Systematic review. Sample population Peer‐reviewed, English‐language articles describing surgical treatments for elbow osteoarthritis in dogs.
Alexandria J. Yu, André J. Nault, Wanda J. Gordon‐Evans   +2 more
wiley   +1 more source

Combining canine mesenchymal stromal cells and hyaluronic acid for cartilage repair [PDF]

Genetics and Molecular Biology
Cell therapy and tissue engineering have been intensively researched for repair of articular cartilage. In this study, we investigated the chondrogenic potential of canine adipose-derived mesenchymal stromal cells (ASCs) combined to high molecular weight
Maria Inês Wits, Gabriela Cabanas Tobin, Maiele Dornelles Silveira, Karine Gehlen Baja, Luisa Maria Macedo Braga, Patricia Sesterheim, Melissa Camassola, Nance Beyer Nardi   +7 more
doaj   +2 more sources

International Veterinary Epilepsy Task Force recommendations for a veterinary epilepsy-specific MRI protocol [PDF]

, 2015
Epilepsy is one of the most common chronic neurological diseases in veterinary practice. Magnetic resonance imaging (MRI) is regarded as an important diagnostic test to reach the diagnosis of idiopathic epilepsy.
A Bathen-Noethen, A Ciantis De, A Pakozdy, AA Raymond, AJ Hall, AK Shah, Akos Pakozdy, AM McIntosh, Andrea Fischer, Andrea Tipold, AR Deibler, CJ Abramson, Clare Rusbridge, DK Thompson, E Wagner, Edward E. Patterson, EJ Ives, EL So, F Cendes, F Rosenow, GS Berns, GS Berns, H Goldberg, Heidrun Potschka, Holger A. Volk, I Craven, J Laothamatas, J Oertzen Von, J Velmurugan, J Wellmer, J Wellmer, Jacques Penderis, Jelena Jovanovik, JS Duncan, JW Wheless, K Ono, Karen Muñana, Kaspar Matiasek, KL Stadler, KM Casey, KM Fiest, L Gygax, L Heske, L Kearsley-Fleet, LM Mellema, LS Garosi, Luisa De Risio, M Guye, M Konar, M Schwartz, Marjorie Milne, ME Milne, Mette Berendt, Michael Podell, MJ Fernandes, MS Anaya Garcia, N Farid, N Ogata, NK Focke, O Jacqmot, P Singh, P Szmuk, PF Cook, PM Smith, PT Wei, R Goncalves, R Kuzniecky, R Neppl, R Vasta, R Viitmaa, R Viitmaa, RA Thames, RL Wolf, Robyn G. Farqhuar, S Hecht, S Mizoguchi, S Torisu, Sam Long, SD Shorvon, Simon Platt, Sofie F. M. Bhatti, SP Knowler, T Guadalupe, T Hammen, T Kuwabara, TJ Oertzen von, TS Jokinen, U Ebert, V Jantti, V Martle, Veronika M. Stein, WD Gaillard, YM Lim, YS Ding, Z Haneef   +94 more
core   +6 more sources

Femoral Head and Neck Excision for Post‐Traumatic Coxofemoral Instability and Capital Physeal Fracture in a Dog: A Case Report

Case Reports in Veterinary Medicine, Volume 2026, Issue 1, 2026.
Post‐traumatic coxofemoral instability and capital physeal fractures are significant orthopedic conditions in dogs that result in joint instability, pain, and functional impairment. In severe or complicated cases, femoral head and neck excision (FHNE) may be indicated as a salvage surgical procedure, particularly when other reconstructive options are ...
Aryelle Skarllat Monteiro Barbosa, Gabriel Monteiro Barbosa, Dana Pusta   +2 more
wiley   +1 more source

The use of intra-articular aneshesia as a diagnostic tool in canine lameness [PDF]

, 2012
Lameness in dogs may be difficult to localize because of mild pathologic changes or inconclusive clinical findings. Intra-articular anesthesia is proposed as a diagnostic method to localize the source of lameness.
Mosselmans, Lynn, Samoy, Yves, Van Ryssen, Bernadette, Van Vynckt, Delphine, Verhoeven, Geert, Verschooten, Francis   +5 more
core   +1 more source

Intervertebral Disc Proteoglycans: Multifunctional Tissue Stabilizing and Instructional Cell Regulatory Proteins That Control Tissue Homeostasis

JOR SPINE, Volume 8, Issue 4, December 2025.
Matrix and cell‐associated proteoglycans are important tissue‐stabilizing, weight‐bearing, and tension‐resisting proteins in the intervertebral disc. Their glycosaminoglycan components have growth factor binding and cell‐instructive properties that allow cells to regulate tissue composition and function.
James Melrose
wiley   +1 more source

Kinetic gait analysis in English Bulldogs

Acta Veterinaria Scandinavica, 2017
Background Canine breed conformation may interfere with locomotion and may predispose to orthopedic disease. Bulldogs have a high incidence of orthopedic diseases such as hip dysplasia.
Andrés Sebastian Aristizabal Escobar, Alexandre Navarro Alves de Souza, Ana Carolina Brandão de Campos Fonseca Pinto, Julia Maria Matera   +3 more
doaj   +1 more source