Results 91 to 100 of about 101,730 (266)

Goal-directed haemodynamic therapy during elective total hip arthroplasty under regional anaesthesia.

, 2011
INTRODUCTION: Total hip replacement is one of the most commonly performed major orthopaedic operations. Goal-directed therapy (GDT) using haemodynamic monitoring has previously demonstrated outcome benefits in high-risk surgical patients under general ...
Michele Divella, Della Rocca, G, Nicola Langiano, Nicola Fasano, COSTA, Maria Gabriella, DELLA ROCCA, Giorgio, Fasano, N, Maria G Costa, Cecconi, M, Maurizio Cecconi, Divella, M, RHODES A, Rhodes, A, DIVELLA M, Costa, MG, Giorgio Rocca, FASANO N, CECCONI M, LANGIANO N, Langiano, N, Andrew Rhodes   +20 more
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Reverse Engineering and Performance Evaluation of a Pump Impeller Fabricated With Additive Manufacturing

Chemie Ingenieur Technik, EarlyView.
This study explores the process chain for reverse engineering and additive manufacturing of a water pump impeller in a process plant. Key aspects include digital twin creation, CAD redesign, material certification, Hirtisation postprocessing, and performance testing. Insights highlight iterative design for improved precision and reliability.
Michael Stadler, Kati Schatz, Sebastian Rehfeldt, Harald Klein   +3 more
wiley   +1 more source

Imaging of hip trauma - occult, suspect and concomitant fractures

, 2016
Background: Between one and nine percent of all hip fractures are occult or suspect and further examinations with computed tomography (CT) and/or magnetic resonance imaging (MRI) are vital for further handling.
Collin, David
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Fragility fractures of the lower limb beyond the hip: A descriptive prospective cohort study

There is an increased recognition that geriatric low-energy lower-limb fragility fractures may have comparatively significant morbidity and mortality as do geriatric hip fractures. Existing literature suggests that these patients may be at least as frail
Shuyu Chen, Julia Poh Hwee Ng, Ivan Tjun Huat Chua, Sean Wei Loong Hong, Rani Ramason   +4 more
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The design, manufacture and analysis of a new implant for fracture fixation in human and veterinary orthopaedic surgery: the bone fastenerod [PDF]

, 2002
Fracture fixation in humans and animals has troubled surgeons and scientists since first it was attempted right up to the present day. At every milestone of achievement in the understanding and practice of fracture repair there has remained a significant
McCartney, William T.
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Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović, Ingrid Tomljanović, Wieke H. Grievink, Diana R. Pereira, Michelle Osse, Peter van Balen, Maria J. Juachon, Marieke L. de Kam, Lisa Pagan, Manon A.A. Jansen, Matthijs Moerland, Jacobus J. Bosch   +11 more
wiley   +1 more source

Hip fracture

BMJ, 2006
Martyn, Parker, Antony, Johansen
openaire   +3 more sources

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

Clinical Pharmacology &Therapeutics, EarlyView.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel, Lars M.G. Smits, Philip H.C. Kremer, Geert Jan Groeneveld   +3 more
wiley   +1 more source

Discontinuing Long‐Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?

Clinical Pharmacology &Therapeutics, EarlyView.
Discontinuation of denosumab (Dmab) may be necessary due to adverse events or an unfavorable long‐term risk–benefit profile. However, accumulating evidence demonstrates pronounced rebound phenomena after withdrawal, most notably a marked increase in multiple vertebral fractures, and, in some reports, elevated mortality.
Ko‐Hsiu Lu, Renn‐Chia Lin, Ing‐Lin Chang, Shau‐Huai Fu, Meng‐Ying Tsai, Shun‐Fa Yang   +5 more
wiley   +1 more source

Estimating the prevalence of osteoporosis in Australia [PDF]

, 2014
This report presents information about the prevalence and impact of osteoporosis in Australians aged 50 and over. Summary Osteoporosis, a common condition among older people, causes bones to become weak.

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