Results 61 to 70 of about 657,288 (235)

Epidemiology of Traumatic Posterior Hip Instability in the National Football League

Orthopaedic Journal of Sports Medicine, 2021
Background: There is a paucity of literature regarding injury incidence, mechanism, and return to play in National Football League (NFL) players who have sustained traumatic posterior hip instability.
Jakob Ackermann MD, Vishal Saxena MD, Jim Whalen ATC, Christina D. Mack PhD, MSPH, Mackenzie Herzog PhD, Jessica R. Probst MPH, Mark D. Price MD, PhD   +6 more
doaj   +1 more source

Time History Gaussian Process Regression for Modeling the Dynamics of Ankle Exoskeleton User Comfort

Advanced Robotics Research, EarlyView.
Exoskeletons need to be comfortable, but the perception of comfort may change over time. This study investigated if short‐term time history directly influences comfort. No previous trials’ input features were predictive of comfort. Including the previous trial's comfort score marginally improved model accuracy compared to a model using only the current
Axl Maberry, Bo Cheng, Anne E. Martin
wiley   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Risk Analysis between Hip Strength with Hamstring Injuries among Professional Youth Footballers in a Single Malaysian Football Club [PDF]

Malaysian Orthopaedic Journal
Introduction: There is paucity of research regarding the incidence of hamstring injuries and its inherent causes within youth Malaysian football contexts.
Azwan-Aziz M, Yunus MY, Ahmad-Shushami AH   +2 more
doaj   +1 more source

Risk factors for overuse injuries in a cohort of elite Swedish track and field athletes

BMC Sports Science, Medicine and Rehabilitation, 2021
Background Most injuries in track and field are caused by overuse with conflicting reports concerning the underlying mechanisms. The purpose of this study was to evaluate how biomechanical and clinical factors relate to the risk of overuse injuries, and ...
Andreas Lundberg Zachrisson, Andreas Ivarsson, Pia Desai, Jon Karlsson, Stefan Grau   +4 more
doaj   +1 more source

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Establishing a range of motion boundary for total hip arthroplasty [PDF]

, 2011
Range of motion of the hip joint is a major contributor to dislocation post total hip replacement. Impingement is often treated as a surrogate for dislocation and occurs – prosthetically – when the neck of the femoral component contacts with the rim of ...
D R Griffin, S M Y Ahmed, Ahmed, S. M. Y., M A Williams, Griffin, Damian R., G A Turley, Turley, Glen A., Williams, M. A. (Mark A.)   +7 more
core   +1 more source

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

Advanced Science, EarlyView.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai, Tao Xu, Rui Ma, Weikun Meng, Shutao Gao, Yakefu Abulizi, Alafate Kahaer, Chuanhui Xun, Maierdan Maimaiti, Rui Cao, Weidong Liang, Polati Maimaiti, Qiang Deng, Jun Sheng, Ting Wang, Mingchong Liu, Weibin Sheng   +16 more
wiley   +1 more source

Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury

Advanced Science, EarlyView.
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang, Yaozhi He, Yanjiao Wang, Jingjing Zhang, Qishun Liang, Mengxian Jia, Yumin Wu, Zongjie Yuan, Ziwei Fan, Yuxuan Li, Huihui Zhang, Qinjiao Fu, Ying Wang, Zhihui Huang, Honglin Teng   +14 more
wiley   +1 more source