Results 41 to 50 of about 31,119 (232)

Tranexamic Acid in Lower Extremity Endoprosthetic Reconstruction for Oncologic Indications: A Retrospective Comparative Study of 617 Patients

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives While tranexamic acid (TXA) reduces blood loss in orthopedic surgery, thromboembolic concerns in cancer patients have limited adoption in orthopedic oncology. This study evaluated TXA efficacy and safety in patients undergoing endoprosthetic reconstruction for oncologic indications.
Stephen W. Chenard, Akhil Rekulapelli, Riley S. Gilbertson, Connor S. Charton, William F. Hefley, Michael J. Colello, Jennifer L. Halpern, Herbert S. Schwartz, Daniel J. Johnson, Jonathan G. Schoenecker, Joshua M. Lawrenz   +10 more
wiley   +1 more source

Valproic Acid Inhibits Ferroptosis and Improves Bone Integration in OVX Rats Through the AMPK/SIRT1 Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The prevalence of postmenopausal osteoporosis (PMOP) has been steadily increasing. Ferroptosis has been recognized as a critical factor influencing the bone‐forming ability of bone marrow mesenchymal stem cells (BMSCs). Valproic acid (VPA), an HDAC inhibitor, has been suggested to play a role in regulating osteoporosis development; however ...
Qing‐Song Gu, Yi‐Fan Gu, Jian‐Qiao Li, Yi‐Heng Li, Yu‐Hu Chen, Lin‐Hui Wang, Zi‐Ru Wang, Yi‐Cong Wang, Min Yang   +8 more
wiley   +1 more source

Step‐by‐step insight into gait analysis: A narrative review unlocking knee biomechanics

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Gait analysis offers a powerful tool for clinical and orthopaedic decision‐making. By quantifying spatiotemporal, kinematic and kinetic parameters during walking, it provides a dynamic window into joint function that static imaging cannot capture.
Giovanni Spallone, Letizia Mancini, Arianna Carnevale, Stefano Campi, Alessandro de Sire, Emiliano Schena, Pieter D'Hooghe, Michael T. Hirschmann, Rocco Papalia, Umile Giuseppe Longo   +9 more
wiley   +1 more source

Revision Total Hip Arthroplasty Complicated by Metastatic Malignant Gastrointestinal Stromal Tumour

Journal of Orthopaedics, Trauma and Rehabilitation, 2014
Periprosthetic malignancy causing failure of total hip arthroplasty is a rare entity. Metastasis of malignant tumour to the proximity of orthopaedic implants is even more uncommon.
Hok-Yin Alwin Li, Pang-Hei Li, Yiu-Chung Wong, Yuk-Leung Wai   +3 more
doaj   +1 more source

Unrestricted kinematic alignment on the sagittal plane: Posterior tibial slope and combined flexion do not have boundaries to respect in terms of short‐term clinical outcomes and safety

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Personalized alignment in total knee arthroplasty (TKA) is gaining traction as a surgical philosophy. True personalization, however, must encompass not only the coronal plane but also the sagittal and axial planes. This study evaluates influence of the Tibial Slope (PTS) and combined flexion (CF) on outcomes in TKA performed using ...
Edoardo Franceschetti, Pietro Gregori, Stefano Campi, Marco Spatuzzi, Giancarlo Giurazza, Andrea Tanzilli, Biagio Zampogna, Matteo Formica, Umile Giuseppe Longo, Rocco Papalia   +9 more
wiley   +1 more source

Efficacy of functional alignment in total knee arthroplasty in restoring in vivo cruciate ligament forces and knee kinematics compared with mechanical alignment

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The impact of coronal alignment on cruciate ligament forces in bicruciate‐retaining total knee arthroplasty (TKA) remains unclear. We aimed to clarify in vivo cruciate ligament forces and knee kinematics among mechanically aligned (MA) and functionally aligned (FA) TKAs and normal knees.
Kenichi Kono, Hiroshi Inui, Tomofumi Kage, Takaharu Yamazaki, Shuji Taketomi, Darryl D'Lima, Tetsuya Tomita, Sakae Tanaka   +7 more
wiley   +1 more source

Dynamic coronal plane knee alignment: Femoral anatomy determines kinematic curve morphology, tibial anatomy determines curve position

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose A single hip–knee–ankle angle (HKA) angle does not reflect the biomechanics of native, arthritic or prosthetic knees. Since HKA varies throughout flexion, dynamic coronal alignment is best represented by a kinematic curve plotting HKA against the range of motion.
Petros Ismailidis, Anthony Leicht, Kenji Doma, Peter McEwen   +3 more
wiley   +1 more source

Prior osteosynthesis—unlike osteotomy—raises revision risk after total knee arthroplasty, predominantly via periprosthetic infection

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Previous knee surgery is discussed as a risk factor for total knee arthroplasty (TKA), yet most reports do not distinguish between osteotomy and osteosynthesis. The German Operationen‐ und Prozedurenschlüssel (OPS)‐based classification was used to compare the impact of these procedures on implant survival, mortality and complications ...
Nele Wagener, Yinan Wu, Alexander Grimberg, Christian Hipfl, Sebastian Hardt   +4 more
wiley   +1 more source

A pilot study: development of bonepreserving- biomimetic artificial femoral head cover

Current Directions in Biomedical Engineering, 2020
Patients with hip arthrosis are increasing each year where total hip replacement is an effective solution when other non-invasive or surgical methods are no longer an effective solution.
Siroros Nad, Liu Yu, Lecouturier Sophie, Tingart Markus, Eschweiler Jörg   +4 more
doaj   +1 more source

Patients with previous anterior cruciate ligament reconstruction achieve equally good outcomes after total knee arthroplasty: A Swedish registry‐based study of 7755 patients

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Patients who have undergone anterior cruciate ligament reconstruction (ACLR) may later require total knee arthroplasty (TKA) due to osteoarthritis (OA). The impact of previous ACLR on patient‐reported outcomes (PROs) after TKA remains uncertain.
Ioannis Syrikas, Ioannis Karikis, Neel Desai, Georgios Tsikandylakis   +3 more
wiley   +1 more source