Results 61 to 70 of about 690,476 (284)

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Contrast Enhanced Ultrasound of Pancreatic Tumours

, 2009
Learning Objectives To describe Contrast Enhanced Ultrasound (CEUS) findings that allow characterization of pancreatic tumours. Imaging Findings Ductal adenocarcinoma: poor enhancement appearing hypoechoic.
D'ONOFRIO, Mirko
core   +1 more source

“ICODE Hip US Calculator”: a mobile phone aid for screening with Graf’s sonographic technique

Journal of Ultrasonography
Aiming to offer a diagnostic tool to aid examiners with correct hip typing and decision-making about patient management, members of the Board of the International Interdisciplinary Consensus Committee on DDH Evaluation (ICODE – https://www.icode.expert),
Chlapoutakis Konstantinos, O’Beirne Joseph, Dubs Beat, Maizen Claudia, Placzek Sonja, Tzatzairis Themistoklis, Casini Carolina   +6 more
doaj   +1 more source

Screening for developmental dysplasia of the hip in Greece: current practice and future perspectives [PDF]

Exploration of Musculoskeletal Diseases
Screening for developmental dysplasia of the hip (DDH) in Greece is being performed according to the guidelines issued by the Institute of Child Health in 2015.
Konstantinos Chlapoutakis, Stylianos Kolovos, Eleni Pippidi, Rozalia Dimitriou, Nikolaos Skoulikaris, Maria Raissaki   +5 more
doaj   +1 more source

A randomised controlled trial of total hip arthroplasty versus resurfacing arthroplasty in the treatment of young patients with arthritis of the hip joint [PDF]

, 2010
Background: Hip replacement (arthroplasty) surgery is a highly successful treatment for patients with severe symptomatic arthritis of the hip joint. For older patients, several designs of Total Hip Arthroplasty have shown excellent results in terms of ...
Costa, Matthew L., Parsons, Nicholas R., Richard P Edlin, Damian R Griffin, Edlin Richard P, Achten, Juul, Achten, J., Edlin, Richard P., Matthew L Costa, Achten Juul, Nick R Parsons, Parsons Nick R, Griffin, Damian R., Edlin, R.P., Griffin, D.R., Costa, M.L., Costa Matthew L, Griffin Damian R, Juul Achten, Parsons, N.R.   +19 more
core   +2 more sources

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Hip Joint Injections: Ultrasound

, 2016
Hip pain is a common presentation in medical practice, and causes include osteoarthritis, rheumatoid arthritis, congenital hip abnormalities, and trauma. Chronic hip pain significantly alters the patient’s quality of life and commonly leads to disability
Hariharan Shankar, Marina Vardanyan
core   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Magnetic resonance imaging in the evaluation of suspected hip sepsis in children

Journal of Children's Orthopaedics, 2022
Background: Rapid and accurate diagnosis of musculoskeletal infection in children is critical to enable appropriate, targeted surgical interventions. Distinguishing between septic arthritis, myositis, and osteomyelitis around the hip can be difficult ...
Nicole Corin, Simon Bennet, Joshua Hill, Simon Thomas   +3 more
doaj   +1 more source

Differential Tissue‐Coupled Powering for Battery‐Free Injectable Electroceuticals

Advanced Science, EarlyView.
A thread‐like injectable neural stimulator is powered through differential tissue‐coupled powering (DTCP), which harvests RF‐frequency tissue potentials with an elongated receiver while preserving a injectable cross‐section. The system integrates an ASIC, stimulation electrodes, and a portable transmitter, enabling wireless peripheral nerve stimulation,
Han Wu, Sultan Mahmud, Mali Halac, Asif Iftekhar Omi, Domenica Sofia Baez Rodas, Jeremiasz Dados, Chaojun Cheng, Anyu Jiang, Cameron Wallace, Anvi Singh, Erin Patrick, Baibhab Chatterjee, Shriya Srinivasan, Adam Khalifa   +13 more
wiley   +1 more source