Results 31 to 40 of about 11,328 (118)

Characterization of the Population With Intermediate‐Risk Status in Pulmonary Arterial Hypertension: Patients in a Latin American Country: The CAPRI Registry

Pulmonary Circulation, Volume 15, Issue 3, July 2025.
ABSTRACT Pulmonary arterial hypertension (PAH) in intermediate‐risk patients poses a challenge for clinicians, particularly in determining the optimal timing for escalating pharmacological treatment. We conducted a multicenter cross‐sectional study that analyzed data from the Colombian Pulmonary Hypertension Network (HAPredCO) on patients diagnosed ...
R. Conde‐Camacho, M. Orozco‐Levi, A. Londoño, R. Gómez‐Palau, E. Tuta‐Quintero, A. Naranjo, K. Díaz, J. De Luque, S. Goldfeder, L. F. Giraldo‐Cadavid, M. C. Guerrero, Red Colombiana de Hipertensión Pulmonar – HAPredCo.   +11 more
wiley   +1 more source

Encapsulation of Carvedilol in Nanomicelles Improves Central Hemodynamics and Target Organ Damage Protection in Spontaneously Hypertensive Rats

Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
ABSTRACT The hypothesis of this work was that chronic treatment with carvedilol (CAR) administered in a nanomicelles‐based formulation (CAR‐NMs), which increases CAR oral bioavailability, is more effective than a conventional liquid CAR formulation (CAR‐LCF) and is comparable to chronic treatment with losartan (LOS) in improving hemodynamic parameters ...
Luciano Parola, Paula Denise Prince, Javier Alberto Walter Opezzo, Jennifer Riedel, Miguel Ángel Allo, Yanina Alejandra Santander Plantamura, Eliana P. Bin, Germán E. González, Andrea Carranza, Martín Donato, Diego A. Chiappetta, Marcela A. Moretton, Christian Höcht   +12 more
wiley   +1 more source

Rethinking the Diagnosis and Management of Antibody‐Mediated Rejection in Multidisciplinary Transplant Meetings: A Global Survey and Banff Working Group Recommendations

Clinical Transplantation, Volume 39, Issue 5, May 2025.
ABSTRACT Introduction The diagnosis of antibody‐mediated rejection (AMR) requires input from several transplant professionals. Bringing clinical and laboratory experts together may help standardize care. Yet, little is known about current global practices of multidisciplinary meetings for AMR management.
Ruth Sapir‐Pichhadze, Medhat Askar, Matthew Cooper, Lynn D. Cornell, Emanuele Cozzi, Darshana M. Dadhania, Fritz Diekmann, Aiko P. J. de Vries, Carrie A. Schinstock, Robert P. Carroll, Ahmad Abdelrehim, Geliang Gan, Yanhong Deng, Sami Alasfar, Serena M. Bagnasco, Ibrahim Batal, Klemens Budde, Marian C. Clahsen‐van Groningen, Vanderlene L. Kung, Fritz Lower, Mariana Seija, Edward Kraus, Maarten Naesens, Laurine M. Bow, the Banff Antibody‐Mediated Injury Working Group   +24 more
wiley   +1 more source

Identification and study of new NF‐κB‐inducing kinase ligands derived from the imidazolone scaffold

Archiv der Pharmazie, Volume 358, Issue 1, January 2025.
A new family of NF‐κB‐inducing kinase (NIK) ligands bearing an imidazolone moiety were synthesized. The best compound showed a dose‐dependent inhibition of p100 to p50 processing in cellular assays, a key step in nuclear factor κB (NF‐κB) activation. Based on computational techniques, a plausible binding mode is proposed.
Francisco Maqueda‐Zelaya, Lara Valiño‐Rivas, Ana Milián, Sara Gutiérrez, José Luis Aceña, Javier Garcia‐Marin, Mª Dolores Sánchez‐Niño, Juan J. Vaquero, Alberto Ortiz   +8 more
wiley   +1 more source

Cardiopulmonary Exercise Testing With Simultaneous Echocardiography After Pulmonary Embolism

Pulmonary Circulation, Volume 15, Issue 1, January 2025.
ABSTRACT Although current guidelines recommend standard cardiopulmonary exercise testing (CPET) to evaluate symptomatic patients after pulmonary embolism (PE), CPET with simultaneous echocardiography could provide relevant information to evaluate right ventricular–pulmonary arterial coupling.
Karys Khilzi, Lucilla Piccari, Gerard Franco, Anna Rodó‐Pin, Anna Herranz, Isabel Blanco, Giuseppe Paciocco, Lorenzo Volpiano, Jose Gonzalez Garcia, Ana Diez‐Llaneza, Lluis Molina, Diego A. Rodríguez Chiaradía   +11 more
wiley   +1 more source

Association of Total Mortality and Cardiovascular Endpoints With the Timing of the First and Second Systolic Peak of the Aortic Pulse Wave

The Journal of Clinical Hypertension, Volume 27, Issue 1, January 2025.
ABSTRACT Prognostic significance of the timing in the cardiac cycle of the first (TP1) and second (TP2) systolic peak of the central aortic pulse wave is ill‐defined. Incidence rates and standardized multivariable‐adjusted hazard ratios (HRs) of adverse health outcomes associated with TP1 and TP2, estimated by the SphygmoCor software, were assessed in ...
Yi‐Bang Cheng, De‐Wei An, Lucas S. Aparicio, Qi‐Fang Huang, Yu‐Ling Yu, Chang‐Sheng Sheng, Teemu J. Niiranen, Fang‐Fei Wei, José Boggia, Katarzyna Stolarz‐Skrzypek, Natasza Gilis‐Malinowska, Valérie Tikhonoff, Wiktoria Wojciechowska, Edoardo Casiglia, Krzysztof Narkiewicz, Wen‐Yi Yang, Jan Filipovský, Kalina Kawecka‐Jaszcz, Ji‐Guang Wang, Tim S. Nawrot, Yan Li, Jan A. Staessen, the International Database of Central Arterial Properties for Risk Stratification (IDCARS) Investigators   +22 more
wiley   +1 more source

American registry of ambulatory and acute decompensated heart failure (AMERICCAASS registry): Rationale and design

ESC Heart Failure, Volume 11, Issue 6, Page 3805-3813, December 2024.
Abstract Aims Heart failure (HF) is a highly prevalent and progressive condition associated with significant morbidity and mortality rates. Acute decompensated HF precipitates millions of hospitalizations each year. Despite therapeutic advances, the overall prognosis of HF is poor. The varying clinical courses and outcomes of patients with this disease
Juan Esteban Gómez‐Mesa, Juliana María Gutiérrez‐Posso, Manuela Escalante‐Forero, David Esteban Eraso‐Bolaños, Mark H. Drazner, Daniel Quesada‐Chaves, Alexander Romero‐Guerra, Eduardo R. Perna, Amada Álvarez‐Sangabriel, Víctor Rossel, Walter Alarco, Mario Speranza   +11 more
wiley   +1 more source

Intermanufacturer assessment of diagnostic performance of angiogenic ratio vs glycosylated fibronectin in women with suspected pre‐eclampsia

Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 5, Page 620-625, November 2024.
ABSTRACT Objective To compare the diagnostic performance of different manufacturers' immunoassays for the soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio with that of a point‐of‐care (PoC) test for glycosylated fibronectin (GlyFn) in women with suspected pre‐eclampsia (PE).
I. Y. M. Wah, D. S. Sahota, N. K. L. Wong, N. M. W. Lee, C. J. Liu, C. S. L. Lau, H. H. Y. Leung, L. C. Poon   +7 more
wiley   +1 more source

Postnatal outcome following fetal aortic valvuloplasty for critical aortic stenosis

Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 3, Page 339-347, September 2024.
ABSTRACT Objective To report our experience of fetal aortic valvuloplasty (FAV) for critical aortic stenosis (AS), with a focus on the postnatal evolution of the patients. Methods This was a retrospective study including all fetuses with critical AS which underwent FAV in a single center between January 2011 and June 2022.
R. Corroenne, M. Meot, L. J. Salomon, I. Szezepanski, H. Baghdadi, B. Stos, M. Levy, J. Le Bidois, D. Laux, R. Gaudin, O. Raisky, Y. Ville, D. Bonnet, J. Stirnemann, S. Malekzadeh‐Milani   +14 more
wiley   +1 more source

Guía de actuación para el farmacéutico comunitario en pacientes con hipertensión arterial y riesgo cardiovascular: Documento de consenso

Farmacéuticos Comunitarios, 2011
La hipertensión arterial (HTA) es un problema de salud estrechamente relacionado con un aumento del riesgo de padecer una enfermedad cardiovascular. Además, la HTA puede producir o empeorar la lesión de ciertos órganos diana, lo que también puede influir
Sabater Hernández D, de la Sierra A, Bellver Monzó O, Divisón JA, Gorostodi M, Perseguer Torregosa Z, Segura J, Tous S   +7 more
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