Results 221 to 230 of about 41,234 (255)
Some of the next articles are maybe not open access.
Hippocampus, hippocampal sclerosis and epilepsy
Pharmacological Reports, 2013Hippocampal sclerosis (HS) is considered one of the major pathogenic factors of drug-resistant temporal lobe epilepsy. HS is characterized by selective loss of pyramidal neurons - especially of sectors CA1 and CA3 of the hippocampus - pathological proliferation of interneuron networks, and severe glia reaction. These changes occur in the course of long-
Sendrowski, Krzysztof +1 more
openaire +2 more sources
Epilepsies associated with hippocampal sclerosis
Acta Neuropathologica, 2014Hippocampal sclerosis (HS) is considered the most frequent neuropathological finding in patients with mesial temporal lobe epilepsy (MTLE). Hippocampal specimens of pharmacoresistant MTLE patients that underwent epilepsy surgery for seizure control reveal the characteristic pattern of segmental neuronal cell loss and concomitant astrogliosis.
Fernando, Cendes +4 more
openaire +2 more sources
Hippocampal sclerosis—Origins and imaging
Epilepsia, 2012SummaryThe association between hippocampal sclerosis (HS) and epilepsy has been known for almost two centuries. For many years, HS was studied in postmortem series; however, since the mid‐20th century, surgical specimens from temporal lobe resections have provided important new knowledge. HS is the most common pathology underlying drug‐resistant mesial
Kristina, Malmgren, Maria, Thom
openaire +2 more sources
Clinical Aspects of Hippocampal Sclerosis
2008Publisher Summary This chapter emphasizes that hippocampal sclerosis (HS) occurs in a variety of clinical settings, including epilepsy and hypoxia/ischemia. HS is also clearly linked to dementia. It is a common pathological finding in autopsied dementia samples, occurring in up to 16% of cases. The chapter focuses on the two major dementing syndromes
James B, Leverenz, Anne M, Lipton
openaire +2 more sources
Hippocampal Sclerosis and Human Memory
Archives of Neurology, 1993To study the effects of hippocampal sclerosis on preoperative neuropsychological memory tests.Analyses of variance and chi 2 tests were used to compare patient groups (divided retrospectively) with a control group.Hospital epilepsy unit.All patients who underwent a temporal lobectomy for intractable seizure relief during the preceding 18 months were ...
L A, Miller, D G, Muñoz, M, Finmore
openaire +2 more sources
Thinking outside the box: non-canonical targets in multiple sclerosis
Nature Reviews Drug Discovery, 2022Orhan Aktas, Tobias Ruck, Michael Roden
exaly