Results 251 to 260 of about 511,468 (345)

Characteristics, therapeutic pathway and the economic burden of patients with drug‐resistant epilepsy: A real‐world analysis following the introduction of cenobamate in Italy

Epilepsia, EarlyView.
Abstract Objectives Drug‐resistant epilepsy (DRE) remains a major clinical challenge, affecting approximately one‐third of patients with epilepsy. Cenobamate, a novel antiseizure medication (ASM) approved in Italy in 2022, has shown promise in clinical trials. However, real‐world data on its use, especially economic evaluations, remain limited.
Valentina Perrone, Chiara Veronesi, Maria Cappuccilli, Margherita Andretta, Marcello Bacca, Antonietta Barbieri, Fausto Bartolini, Alessandro Brega, Maria Rosaria Cillo, Francesco Colasuonno, Stefania Dell'Orco, Fulvio Ferrante, Stefano Grego, Antonella Lavalle, Daniela Mancini, Maurizio Pastorello, Romina Pagliaro, Cataldo Procacci, Camilla Scandolara, Patrizia Schiavone, Loredana Ubertazzo, Paola Valpondi, Adriano Vercellone, Alberto Zucchi, Maria Ciappetta, Domenico Lucatelli, Andrea Cinti Luciani, Luca Degli Esposti   +27 more
wiley   +1 more source

Enlarged perivascular space in the temporal lobe as a prognostic marker in temporal lobe epilepsy with hippocampal sclerosis. [PDF]

Epilepsia
Cho S, Song S, Yum J, Kim EH, Roh YH, Kim WJ, Heo K, Na HK, Kim KM.   +8 more
europepmc   +1 more source

The interacting etiologies of hippocampal sclerosis in epilepsy: A scoping review

Epilepsia, EarlyView.
Abstract According to the International League Against Epilepsy classification, mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is considered an epilepsy syndrome. Several etiologies may precede HS, but there is little overview in the literature about these etiologies.
Boris Deleu, Jules Jeuris, Wim Van Paesschen   +2 more
wiley   +1 more source

Verbal paired associates learning lateralizes left hippocampal sclerosis in temporal lobe epilepsy. [PDF]

Epilepsia Open
Sitoh A, Weintrob D, Anderson JFI, Jackman AR, O'Shea MF, Jackson GD, Perucca P, Tailby C.   +7 more
europepmc   +1 more source

High frequency deep brain stimulation of the hippocampus in a rat model for temporal lobe epilepsy [PDF]

, 2006
Boon, Paul, CLAEYS, P, De Smedt, Tim, Leybaert, Luc, Mabilde, Cyriel, Raedt, Robrecht, Van den broecke, Caroline, Wadman, Wytse, Waterschoot, Liesbeth, Wyckhuys, Tine   +9 more
core   +1 more source

C1q neutralization during epileptogenesis attenuates complement‐mediated synaptic elimination and epileptiform activity

Epilepsia, EarlyView.
Abstract Objective Accumulating evidence indicates that aberrant C1q‐C3 complement signaling in microglia and astrocytes drives synaptic dysfunction and neuronal loss. C1q‐mediated synaptic dysfunction disrupts neuronal circuitry balance and can lead to network hyperexcitability in epilepsy.
Yoonyi Jeong, Hyun‐Kyoung Lim, Hayeon Kim, Juheon Lee, Siyoon Lee, Minah Suh   +5 more
wiley   +1 more source

Temporal Trends in Hippocampal Sclerosis Surgery: An Observational Study From a Tertiary Epilepsy Centre. [PDF]

Eur J Neurol
Vassallo P, Gursal V, Xiong W, Zhou D, de Tisi J, Thijs RD, Duncan JS, Sander JW.   +7 more
europepmc   +1 more source

Value of ultra‐high‐field MRI in patients with drug‐resistant focal epilepsy and negative 3T MRI (EpiUltraStudy): Diagnostic gain of 7T structural analysis

Epilepsia, EarlyView.
Abstract Objective Resective epilepsy surgery is an evidence‐based treatment option for patients with focal drug‐resistant epilepsy (DRE). Seizure outcome after surgery is largely dependent on detection and delineation of an epileptogenic lesion on magnetic resonance imaging (MRI). However, detection fails in 30% of patients at 3 Tesla (T) MRI, thereby
Rick H. G. J. van Lanen, Daniel Uher, Christianne M. C. Hoeberigs, Paul A. M. Hofman, Remco Santegoeds, Christopher Wiggins, Desmond H. Y. Tse, Esther G. M. Steijvers, Jacobus F. A. Jansen, Gerald S. Drenthen, Alard Roebroeck, Dimo Ivanov, Benedikt A. Poser, Sander M. J. van Kuijk, Govert Hoogland, Kim Rijkers, Louis G. L. Wagner, Guido Widman, Jan Beckervordersandforth, Sylvia Klinkenberg, Rob P. W. Rouhl, Daniel Delev, Hans Clusmann, Stefan Wolking, Yvonne Weber, Laurien K. Dhaenens‐Meyer, Elisabeth Schriewer, Alfred Meurs, Katrien Jansen, Tom Theys, Wim van Paesschen, Dirk van Roost, Walter H. Backes, Albert J. Colon, Olaf E. M. G. Schijns, on behalf of the ACE Epilepsy Surgery group, Gwendolyn de Bruyn, Albert Colon, Jim Dings, Marc Hendriks, Danny Hilkman, Christianne Hoeberigs, Jochem van der Pol, Lotte de Jong, Kim Rijkers, Sylvia Klinkenberg, Vivianne van Kranen Mastenbroek, Jeske Nelissen, Pieter Kubben, Walter M. Palm, Rob P. W. Rouhl, Olaf Schijns, Simon Tousseyn, Marielle Vlooswijk, Louis Wagner, Dorien Weckhuysen, Ilse van Straaten   +56 more
wiley   +1 more source

Brain Hypertrophy in Patients With Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis and Its Clinical Correlates. [PDF]

Neurology
Zubal R, Velicky Buecheler M, Sone D, Postma T, De Tisi J, Caciagli L, Winston GP, Sidhu MK, Long L, Xiao B, Mcevoy AW, Miserocchi A, Vos SB, Baumann CR, Duncan JS, Koepp MJ, Galovic M.   +16 more
europepmc   +1 more source

Dissociation between diffusion MR tractography density and strength in epilepsy patients with hippocampal sclerosis

, 2010
Timothy M. Ellmore, Thomas A. Pieters, Nitin Tandon   +2 more
openalex   +2 more sources