HMGB1 dysregulation: a neuroimmune bridge to cognitive impairment in autoimmune thyroiditis. [PDF]
Wang J +5 more
europepmc +1 more source
Abstract Objective Epilepsy surgery is an effective treatment option for patients with medically refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE). The success of surgery depends on the accurate localization of the epileptogenic zone, which can be challenging due to the subtle imaging ...
Jean Khoury +7 more
wiley +1 more source
Neuroprotective properties of <i>Linzia gerberiformis</i> aqueous leaves extract against aluminium chloride (AlCl<sub>3</sub>) -induced cognitive impairment: Involvement of cholinergic, GABAergic, and antioxidant mechanisms. [PDF]
Noubouwo JC +7 more
europepmc +1 more source
Abstract Objective Status epilepticus (SE) is the most severe expression of seizures, encompassing both SE with prominent motor symptoms and nonconvulsive SE (NCSE). Ictal–interictal continuum (IIC), an electroencephalographic phenomenon, is characterized by periodic discharges (PD), spike‐and‐waves or sharp‐and‐waves (SW), or lateralized rhythmic ...
Pilar Bosque‐Varela +15 more
wiley +1 more source
Local synthesis and function of neuro-estrogen and neuro-androgen: impact on the hippocampus-related cognition and neuronal plasticity. [PDF]
Kawato S +5 more
europepmc +1 more source
Abstract Objective Long‐term memory deficits are often seen in patients with temporal lobe epilepsy (TLE). Recently, studies showed that patients with hippocampal sclerosis (HS) type 2, which presents with severe neuron loss in CA1 only, performed within the normal range. However, up to 30% of HS type 2 cases have memory deficits.
Henrique Cruz +10 more
wiley +1 more source
Effects of gonadectomy on brain sex hormone levels and amyloid pathology in male and female App<sup>NL-G-F</sup> and App<sup>NL-F</sup> mice. [PDF]
Muñoz P +10 more
europepmc +1 more source
Amygdala enlargement associated with remote epileptogenic lesions
Abstract Objective To determine the prevalence and possible causes of amygdala enlargement in patients with drug‐resistant temporal lobe epilepsy. Methods Patients were retrospectively identified via a radiology information system and a large language model.
Horst Urbach +5 more
wiley +1 more source
Enhancement of Memory and Synaptic Plasticity by <i>Celastrus paniculatus</i> Seed Extract: Upregulation of pSer831-GluA1 Trafficking and Arc/PSD-95 Expression in the Hippocampus of Male Rats. [PDF]
Thongon N +2 more
europepmc +1 more source
Spatial transcriptomics in epilepsy research: Early successes, opportunities, and challenges
Epilepsia, EarlyView.
Donald J. Phillips +4 more
wiley +1 more source

