Results 81 to 90 of about 600,635 (289)

Verbal paired associates and the hippocampus: The role of scenes [PDF]

open access: yes, 2018
It is widely agreed that patients with bilateral hippocampal damage are impaired at binding pairs of words together. Consequently, the verbal paired associates (VPA) task has become emblematic of hippocampal function.
Clark, I., Kim, M., Maguire, E.
core   +2 more sources

Nanoporous Microelectrodes for Neural Electrophysiology Recordings in Organotypic Culture

open access: yesAdvanced Materials Technologies, EarlyView.
The highly porous microelectrodes have been designed and printed on culture membranes, allowing to record electrophysiological neural activity for rodent brain slices. To keep the biocompatible nanoporous structure, the microelectrodes and insulative layer are fabricated on the bottom of culture membranes with only small connector pads added on the top.
Petro Lutsyk   +3 more
wiley   +1 more source

Synthesis, in silico and Pharmacological Evaluation of New Thiazolidine-4-Carboxylic Acid Derivatives Against Ethanol-Induced Neurodegeneration and Memory Impairment [Retraction]

open access: yesJournal of Inflammation Research, 2022
Naz S, Al Kury LT, Nadeem H, et al. J Inflamm Res. 2022;15:3643–3660. The Editor and Publisher of the Journal of Inflammation Research wish to retract the published article.
Naz S   +7 more
doaj  

Pdxdc1 modulates prepulse inhibition of acoustic startle in the mouse. [PDF]

open access: yes, 2017
Current antipsychotic medications used to treat schizophrenia all target the dopamine D2 receptor. Although these drugs have serious side effects and limited efficacy, no novel molecular targets for schizophrenia treatment have been successfully ...
Boutros, PC   +5 more
core   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang   +4 more
wiley   +1 more source

Dedicated hippocampal inhibitory networks for locomotion and immobility [PDF]

open access: yes, 2017
Network activity is strongly tied to animal movement; however, hippocampal circuits selectively engaged during locomotion or immobility remain poorly characterized.
Arriaga, Moises, Han, Edward B
core   +2 more sources

Predicting Macrophage Spatial Localization from Single‐Cell Transcriptomes to Uncover Disease Mechanisms

open access: yesAdvanced Science, EarlyView.
This study presents a machine‐learning framework entitled MERLIN that infers the microanatomical localization of macrophages from single‐cell transcriptomic data in structured organs such as the kidney and brain. Applying this method to existing datasets from models of acute kidney injury and diabetic nephropathy uncovered spatially resolved insights ...
Junping Yin   +18 more
wiley   +1 more source

A gradient of frequency-dependent synaptic properties along the longitudinal hippocampal axis

open access: yesBMC Neuroscience, 2017
Background The hippocampus is a functionally heterogeneous brain structure and specializations of the intrinsic neuronal network may crucially support the functional segregation along the longitudinal axis of the hippocampus.
Vassilios Papaleonidopoulos   +3 more
doaj   +1 more source

Brain Differences in the Prefrontal Cortex, Amygdala, and Hippocampus in Youth with Congenital Adrenal Hyperplasia [PDF]

open access: yes, 2020
Context: Classical Congenital Adrenal Hyperplasia (CAH) due to 21-hydroxylase deficiency results in hormone imbalances present both prenatally and postnatally that may impact the developing brain.
Azad, Anisa   +5 more
core  

Sleep Alters the Velocity of Physiological Brain Pulsations in Humans

open access: yesAdvanced Science, EarlyView.
Sleep alters I/CSF oscillatory flow, driven by increased respiratory (29%) and vasomotor pulsation (21%) velocities, while cardiovascular pulsations decreased by (22%). Velocity is quantified using optical flow analysis of MREG data. Spectral power increases alongside these pulsations (spatial correlation, r = 0.35 and r = 0.39, respectively ...
Ahmed Elabasy   +13 more
wiley   +1 more source

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