Results 41 to 50 of about 512 (159)
Gut microbiome‐derived metabolites show promise in cancer research and therapy
Interdisciplinary Medicine, Volume 4, Issue 2, March 2026.The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang +4 more
wiley +1 more source
, 2008 Peptidyl alpha-hydroxylating monooxygenase (PHM) functions in vivo towards the biosynthesis of alpha-amidated peptide hormones in mammals and insects. PHM is a potential target for the development of inhibitors as drugs for the treatment of human disease
Carpenter, Sarah E +19 more
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Experimental Biology and Medicine, 1964 Summary1. A method for analysis of microgram quantities of hippuric acid in plasma with good precision and accuracy is presented. 2. There is no significant difference in the clearance of hippuric acid and p-aminohippuric acid by the dog.
H C, ELLIOTT, A A, WALKER
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SYNTHESIS OF HIPPURIC ACID IN LIVER HOMOGENATE
Journal of Biological Chemistry, 1947 The synthesis of hippuric acid from benaoic acid and glycine resembles in several respects the synthesis of a peptide bond. A CONH group is formed, it is a to a carboxyl group, and the free energy of its formation is of the same order of magnitude. The synthesis was demonstrated in liver and kidney slices of a number of animals; it is inhibited by 0 ...
H, BORSOOK, J W, DUBNOFF
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Induced pi-facial discrimination in the alkylation of chiral derivatives of glycine.
, 1999 Part A. The alkylation trans 2-arylcyclohexyl hippurates with a series of electrophiles was examined. The reaction stereoselectivity varied from 46 to 81% depending on the steric and electronic nature of the electrophile when (Ar = phenyl).
Peters, Scott Owen.
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Hippurate participates in the correction of metabolic acidosis
Kidney International, 2001 Hippurate (Hip), an endogenous conjugate, belongs to the group of uremic toxins. Hip stimulates P-independent glutaminase (PIG) localized at the proximal luminal membrane, desamidating glutamine with the formation of ammonia, a dominant and adaptive elimination product of H+.
Dzúrik, Rastislav +3 more
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Protein-Bound Toxins-Update 2009
, 2009 Protein-bound uremic retention solutes constitute a group whose common characteristic is their difficult removal by dialysis. In 2003, the EUTox group described 25 protein-bound solutes.
Jourde-Chiche, N +10 more
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Induced pi-facial discrimination in the alkylation of chiral derivatives of glycine.
, 1998 Part A. The alkylation trans 2-arylcyclohexyl hippurates with a series of electrophiles was examined. The reaction stereoselectivity varied from 46 to 81% depending on the steric and electronic nature of the electrophile when (Ar = phenyl).
Peters, Scott Owen
core +1 more source
Hippurate Hydrolysis in Klebsiella-Cloaca Classification [PDF]
Journal of General Microbiology, 1957 SUMMARY: 169 strains of Klebsiella pneumoniae and 68 strains of Cloaca cloacae were used in an examination of Hajna & Damon's hippurate test and various modifications of it. The addition of a pH indicator (phenol red) to the medium enabled hydrolysis to be detected by a change of colour. Clear-cut distinction between K. pneumoniae and C.
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, 2008 Peptidyl a-hydroxylating monooxygenase (PHM) functions in vivo towards the biosynthesis of a-amidated peptide hormones in mammals and insects. PHM is a potential target for the development of inhibitors as drugs for the treatment of human disease and as ...
M. Romero (11678484) +19 more
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