Results 91 to 100 of about 220,074 (311)
Nature CommunicationsDNA polymerase III sliding clamp (DnaN) was recently validated as a new anti-tuberculosis target employing griselimycins. Three (2 S,4 R)−4-methylproline moieties of methylgriselimycin play significant roles in target binding and metabolic stability ...
Chengzhang Fu +10 more
doaj +1 more source
Precaution, governance and the failure of medical implants: the ASR(TM) hip in the UK [PDF]
, 2014 Hip implants have provided life-changing treatment, reducing pain and improving the mobility and independence of patients. Success has encouraged manufacturers to innovate and amend designs, engendering patient hopes in these devices.
Joyce, Thomas +2 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective Antinuclear antibodies (ANAs) are present at high titers in 2% of the general population, but their clinical significance in individuals without an autoimmune (AI) disease is not known. We tested the hypothesis that the presence of a high ANA titer in non‐AI conditions is associated with disease.
Matthew Chung +7 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti +19 more
wiley +1 more source
Bone & Joint OpenAims: Nonoperative treatment for developmental dysplasia of the hip (DDH) typically involves numerous in-person clinic visits, which can place a significant burden on healthcare services and patients’ families.
Yashvi Verma +4 more
doaj +1 more source
The Thermal Degradation of Nanocomposites That Contain an Oligomeric Ammonium Cation on the Clay [PDF]
, 2004 The thermal degradation of polystyrene, high-impact polystyrene, ABS terpolymer, poly(methyl methacrylate), polypropylene and polyethylene nanocomposites has been studied using thermogravimetric analysis coupled to Fourier transform infrared spectroscopy,
Su, Shengpei, Wilkie, Charles A.
core +1 more source
Arthritis Care &Research, EarlyView.Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi +4 more
wiley +1 more source
Vibratory and conventional impaction of acetabular components into porcine acetabula
Bone & Joint ResearchAims: Sufficient primary implant stability with minimal bone damage is one of the challenges for uncemented implant fixation to prevent periprosthetic fractures and implant loosening.
Yasaman Niki +3 more
doaj +1 more source
Novel Polymerically-Modified Clays Permit the Preparation of Intercalated and Exfoliated Nanocomposites of Styrene and its Copolymers by Melt Blending [PDF]
, 2004 Two new organically-modified clays have been made and used to produce nanocomposites of polystyrene, high impact polystyrene and acrylonitrile–butadiene–styrene terploymer.
Jiang, David D. +2 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source