Results 51 to 60 of about 93,742 (299)

The Exeter Universal cemented femoral stem at 20 to 25 years: A report of 382 hips [PDF]

, 2016
We report a minimum 20-year follow-up study of 382 total hip replacements in 350 patients with mean age 66.3 years (range 17-94) at operation. All patients received the same design of femoral component, regardless of the original diagnosis, 33 (8.6 ...
Hubble, M.J.W., Wilson, M.J., Petheram, T.G., Howell, J.R., Kazi, H.A., Timperley, A.J., Whitehouse, S.L.   +6 more
core   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

HIPs and HIP-reactive T cells [PDF]

Clinical and Experimental Immunology, 2019
Summary Mounting evidence implicates hybrid insulin peptides (HIPs) as important autoantigens in the development of type 1 diabetes (T1D). These fusion peptides formed between insulin and other pancreatic beta cell-derived peptides contain non-genomically encoded amino acid sequences, making them plausible targets for autoreactive T ...
T A Wiles, T Delong
openaire   +2 more sources

Periacetabular osteotomy restores the typically excessive range of motion in dysplastic hips with a spherical head [PDF]

, 2015
BACKGROUND Residual acetabular dysplasia is seen in combination with femoral pathomorphologies including an aspherical femoral head and valgus neck-shaft angle with high antetorsion.
Marc Puls, Young-Jo Kim, Millis, Michael B, Simon D. Steppacher, Puls, Marc, Michael B. Millis, Tannast, Moritz, Corinne A. Zurmühle, Siebenrock, Klaus A, Kim, Young-Jo, Zurmühle, Corinne A, Klaus A. Siebenrock, Steppacher, Simon D, Moritz Tannast   +13 more
core   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Tandem ketone reduction in pepstatin biosynthesis reveals an F420H2–dependent statine pathway

Nature Communications
Pepstatins are potent inhibitors of aspartic proteases, featuring two statine residues crucial for target binding. However, the biosynthesis of pepstatins, especially their statine substructure, remains elusive.
Jingjun Mo, Asfandyar Sikandar, Haowen Zhao, Ghader Bashiri, Liujie Huo, Martin Empting, Rolf Müller, Chengzhang Fu   +7 more
doaj   +1 more source

Dynamic femoral head translations in dysplastic hips. [PDF]

, 2017
BACKGROUND: Developmental dysplasia of the hip is an important disease leading to osteoarthritis. Recently, researchers have focused on hip instability as a potentially important dynamic factor for osteoarthritis, but the detailed kinematics of ...
Sato, Tatsuya, 佐藤, 達也, サトウ, タツヤ   +2 more
core   +1 more source

Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance

Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah, Martha E. Stewart, Nathan Maassel, James P. Stevens, Claudia R. Morris, Chris A. Rees   +5 more
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

New myxobacteria of the Myxococcaceae clade produce angiolams with antiparasitic activities

Microbiology Spectrum
In the past century, microbial natural products have proven themselves to be substantial and fruitful sources of anti-infectives. In addition to the well-studied Actinobacteria, understudied bacterial taxa like the Gram-negative myxobacteria have ...
Sebastian Walesch, Ronald Garcia, Abdelhalim B. Mahmoud, Fabian Panter, Sophie Bollenbach, Pascal Mäser, Marcel Kaiser, Daniel Krug, Rolf Müller   +8 more
doaj   +1 more source