Results 51 to 60 of about 4,891,717 (200)

One-stage Operation for Hirschsprung's Disease: Experience with 192 Cases

Asian Journal of Surgery, 2008
To report early and late outcomes after a one-stage operation for Hirschsprung's Disease (HD). METHODS: Between December 2001 and December 2004, 192 patients (165 boys and 27 girls) underwent a one-stage operation for HD.
Nguyen T. Liem, Bui D. Hau
doaj   +1 more source

Associated congenital heart disease with Hirschsprung's disease: a retrospective cohort study on 2,174 children

Frontiers in Cardiovascular Medicine, 2023
ObjectiveTo examine the incidence and phenotypes of congenital heart disease (CHD) in a large cohort of patients with Hirschsprung's disease (HSCR).Study designRetrospective data review of children with HSCR between 2003 and 2020 was conducted at the ...
Yujian Wu, Yujian Wu, Yun Zhu, Yun Zhu, Xu Zhang, Xu Zhang, Jinqing Feng, Jinqing Feng, Huimin Xia, Huimin Xia, Yan Zhang, Yan Zhang, Jia Li, Jia Li   +13 more
doaj   +1 more source

Adult Onset Hirschsprung's Disease With Overlapping Presentation of Sigmoid Volvulus: Two Case Reports With Literature Review at Tikur Ambessa Specialized Hospital, AAU, Ethiopia

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Adult‐onset Hirschsprung's disease (HSD) is uncommon and frequently leads to diagnostic difficulty after infancy. It is a congenital illness that causes intestinal obstruction due to a lack of ganglion cells. Approximately 1 in 5000 live newborns have this illness, and 95% of HSD cases are identified in infants.
Abel shiferaw Tesfaye, Samson Yadeta Murre, Mikiyas Olani Kebede, Isa Salo Abdo, Mulugeta Temesgen Bonger, Abel Daniel Kuche   +5 more
wiley   +1 more source

Variants of Hirschsprung disease

Seminars in Pediatric Surgery, 2012
Variants of Hirschsprung disease are conditions that clinically resemble Hirschsprung disease, despite the presence of ganglion cells in rectal suction biopsies. The characterization and differentiation of various entities are mainly based on histologic, immunohistochemical, and electron microscopy findings of biopsies from patients with functional ...
Prem, Puri, Jan-Hendrik, Gosemann
openaire   +2 more sources

Familial Experience With Hirschsprung's Disease Improves the Patient's Ability to Cope

Frontiers in Pediatrics, 2022
IntroductionFamilial occurrence of Hirschsprung's disease may have a positive effect on patients' ability to cope with the disease. The aim was to compare long-term bowel function and generic quality of life between patients with familial and non ...
Sanne J. Verkuijl, Sanne J. Verkuijl, Rob J. Meinds, Rob J. Meinds, Alida F. W. van der Steeg, Cornelius E. J. Sloots, Ernst van Heurn, Ivo de Blaauw, Wim G. van Gemert, Marieke J. Witvliet, Karin M. Vermeulen, Monika Trzpis, Paul M. A. Broens, Paul M. A. Broens   +13 more
doaj   +1 more source

Sigmoid Volvulus in a Young Adult With Cerebral Palsy: A Case Managed by the Paul‐Mikulicz Procedure

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 25‐year‐old male with cerebral palsy presented with sigmoid volvulus complicated by ischemia and fecal impaction—an underrecognized but serious risk in this population. Emergency Paul‐Mikulicz colostomy achieved safe resection. Clinicians should suspect volvulus early in CP patients, and proactive bowel management is essential.
Mehwish Saleem, Asad Ahsan, Shahroze Wajid, Muhammad Muaz, Bahzad Akram Khan, Arham Saif, Muhammad Husnain Ahmad   +6 more
wiley   +1 more source

Aberrant Reduction of MiR-141 Increased CD47/CUL3 in Hirschsprung's Disease

Cellular Physiology and Biochemistry, 2013
Background: MiR-141 has been confirmed to be associated with various human diseases. However, whether miR-141 is involved in the pathogenesis of Hirschsprung's disease (HSCR) remains unknown.
Weibing Tang, Jingjing Qin, Junwei Tang, Hongwei Zhang, Zhigang Zhou, Bo Li, Qiming Geng, Wei Wu, Yankai Xia, Xiaoqun Xu   +9 more
doaj   +1 more source

Study on the application of optical coherence microscopy in Hirschsprung's disease

Scientific Reports, 2023
To explore the clinical application value of optical coherence microscopy (OCM) in Hirschsprung’s disease. 109 HSCR patients were recuited in a Chinese hospital from January 2018 to July 2021. All the recruited patients underwent barium enema angiography
Zhiwei Wu, Jialun Song, Xianxu Zeng, Zhenjie Cao, Xinxin Zhao, Peng Wang, Qian Ma, Huan Ma, Baojin Wang, Junpeng Du   +9 more
doaj   +1 more source

Identification of Variants in Two Families With Congenital Cataract by Whole Exome Sequencing

Molecular Genetics &Genomic Medicine, Volume 14, Issue 10, October 2026.
We describe likely pathogenic missense variants causing congenital cataract and investigate these variants using high‐throughput gene sequencing, Sanger sequencing, bioinformatics, and computational biology tools. Our findings provide novel insights into the molecular diagnosis of congenital cataract and have important implications for genetic ...
Yazhou Huang, Xinwei Leng, Jibo Zhang, Xingxin Fang, Ting He, Lihua Zhou, Zhenkai Wu, Yuankun Wang, Dan Peng   +8 more
wiley   +1 more source

RET and PHOX2B genetic polymorphisms and Hirschsprung's disease susceptibility: a meta-analysis. [PDF]

PLoS ONE, 2014
BACKGROUND: Many publications have evaluated the correlation between RET, PHOX2B polymorphisms and Hirschsprung's disease with conflicting results. We performed this meta-analysis to clarify the association of RET, PHOX2B polymorphisms with HSCR. METHODS:
Chun-mei Liang, Dong-mei Ji, Xu Yuan, Ling-ling Ren, Juan Shen, Hai-yan Zhang   +5 more
doaj   +1 more source