Results 111 to 120 of about 20,949 (333)

Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy

Advanced Healthcare Materials, EarlyView.
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley   +1 more source

Tapered Pillar Design for High‐Precision Force Readout in Miniaturized Engineered Heart Tissues From Human Pluripotent Stem Cells

Advanced Healthcare Materials, EarlyView.
Engineered heart tissues (EHTs) are a valuable approach in capturing human cardiac physiology and drug responses in vitro. Here, a novel tapered pillar design is developed in an EHT platform to confine tissues in a predefined position‐ at the middle of the pillar height.
Milica Dostanić, Maury Wiendels, Laura M. Windt, Mervyn P.H. Mol, Francijna E. van den Hil, Richard P. Davis, Valeria Orlova, Berend J. van Meer, Massimo Mastrangeli, Christine L. Mummery   +9 more
wiley   +1 more source

The use of His bundle pacing for the treatment of painful left bundle branch block syndrome

Clinical Case Reports, 2020
Painful left bundle branch block syndrome is a rare disorder in which patients develop typical angina‐like pain without identifiable ischemia. To date, there have been few published cases of effective treatment.
Kevin Andrew Smith, Julie Frey, Amber McKenzie, Kyle Hornsby, John Strobel   +4 more
doaj   +1 more source

His Bundle Pacing: State of the Art

US Cardiology Review, 2018
Traditional right ventricular pacing can be associated with adverse remodeling, leading to left ventricular dysfunction, functional mitral regurgitation, left atrial dilatation, as well as atrial and ventricular arrhythmias. His bundle pacing (HBP) has emerged as a viable and reliable alternative to right ventricular pacing.
Ghulam Muqtada Chaudhry, Matthew F Yuyun
openaire   +2 more sources

Brugada-type Electrocardiographic Pattern Induced by Fever [PDF]

, 2005
ST-segment elevation in Brugada syndrome is caused by a shift in the ionic current balance and the creation of a voltage gradient between the epicardium and the endocardium. This ionic mechanism have been shown to be temperature dependent. We describe a
Aras, Dursun, Deveci, Bulent, Geyik, Bilal, Ozeke, Ozcan, Selcuk, Timur   +4 more
core   +2 more sources

Functionalized Reduced Graphene Oxide‐Based Nanocomposite Hydrogels for Enhanced Osteogenesis in Bone Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Charge‐opposed reduced graphene oxide fillers are co‐integrated into biopolymeric nanocomposite scaffolds, synergistically enhance osteogenesis. Multiscale characterization reveals how surface chemistry and porosity dictate ectopic mineral architecture.
George Mihail Vlăsceanu, Cătălina Ionela Zamfir, Cornel Baltă, Hildegard Herman, Alina Ciceu, Maria Alexandra Duma, Mariana Ioniță, Roxana‐Cristina Popescu, Anca Hermenean   +8 more
wiley   +1 more source

Normalization of the EKG in patients with right bundle branch block by Right ventricular pacing

Majalah Kardiologi Indonesia, 2013
Right ventricle apex (RVA) pacing bypasses the His-Purkinje system result-ing in left bundle branch block like pattern on surface EKG. In preexisting right bundle branch block (RBBB), pacing from certain location of RV might change the EKG pattern.
Z Zainuddin, Yoga Yuniadi, Hardja Priatna, Dicky A Hanafi   +3 more
doaj   +1 more source

Pathophysiology, diagnosis and treatment of tachycardiomyopathy. [PDF]

, 2017
Tachycardiomyopathies (TCMP) are an important cause of left ventricular (LV) dysfunction that should be recognised by physicians as they are potentially reversible and have a significant impact on morbidity and prognosis.
Lambiase, PD, Martin, CA
core   +1 more source

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

Advanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li, Jiahui Li, Hasan Al Faruque, Paul Shami, Birgit Knoechel, Jens Lohr, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček   +8 more
wiley   +1 more source

Shedding Light on the Cellular Uptake Mechanisms of Bioactive Glass Nanoparticles as Controlled Intracellular Delivery Platforms: A Review of the Recent Literature

Advanced Healthcare Materials, EarlyView.
This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda, Aldo R. Boccaccini   +1 more
wiley   +1 more source