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Histamine, histamine intoxication and intolerance.

Allergologia et Immunopathologia, 2015
Excessive accumulation of histamine in the body leads to miscellaneous symptoms mediated by its bond to corresponding receptors (H1-H4). Increased concentration of histamine in blood can occur in healthy individuals after ingestion of foods with high contents of histamine, leading to histamine intoxication.
E. Kovacova-Hanuskova, T. Buday, S. Gavliakova, J. Plevková   +3 more
semanticscholar   +4 more sources

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Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in mice

Science Translational Medicine, 2022
The gut microbiota has been implicated in chronic pain disorders, including irritable bowel syndrome (IBS), yet specific pathophysiological mechanisms remain unclear.
G. De Palma, C. Shimbori, D. Reed, Yang Yu, V. Rabbia, Jun Lu, N. Jimenez-Vargas, J. Sessenwein, C. López-López, M. Pigrau, J. Jaramillo-Polanco, Yong Zhang, Lauren Baerg, Ahmad Manzar, J. Pujo, X. Bai, M. Pinto-Sanchez, A. Caminero, K. Madsen, M. Surette, M. Beyak, A. Lomax, E. Verdú, S. Collins, S. Vanner, P. Bercik   +25 more
semanticscholar   +1 more source

Histamine accumulation in dairy products: Microbial causes, techniques for the detection of histamine-producing microbiota, and potential solutions.

Comprehensive Reviews in Food Science and Food Safety, 2021
Histamine poisoning is a significant public health and safety concern. Intoxication from ingestion of food containing high amounts of histamine may cause mild or severe symptoms that can even culminate in cardiac arrest.
Marta Moniente, D. García-Gonzalo, I. Ontañón, R. Pagán, L. Botello-Morte   +4 more
semanticscholar   +1 more source

Histamine

Clinical Reviews in Allergy, 1983
Histamine is a potent mediator of immediate hypersensitivity reactions, and is stored primarily in mast cells and basophils. It exerts its pharmacologic effects through interactions with H1 and H2 cell surface receptors, which promote changes in vascular permeability, levels of cyclic nucleotides, neutrophil and eosinophil chemokinesis and chemotaxis ...
Zygmunt L. Kruk, Christopher J. Pycock
openaire   +4 more sources

Mast cells activated by SARS-CoV-2 release histamine which increases IL-1 levels causing cytokine storm and inflammatory reaction in COVID-19.

Journal of Biological Regulators and Homeostatic Agents, 2020
SARS-CoV-2 virus is an infectious agent commonly found in certain mammalian animal species and today also in humans. SARS-CoV-2, can cause a pandemic infection with severe acute lung injury respiratory distress syndrome in patients with COVID-19, that ...
P. Conti, A. Caraffa, G. Teté, C. E. Gallenga, R. Ross, S. Kritas, I. Frydas, A. Younes, P. Emidio, G. Ronconi   +9 more
semanticscholar   +1 more source

Current Trends in Detection of Histamine in Food and Beverages.

Journal of Agricultural and Food Chemistry, 2019
Histamine is a heterocyclic amine formed by decarboxylation of the amino acid l-histidine. It is involved in the local regulation of physiological processes but also can occur exogenously in the food supply. Histamine is toxic at high intakes; therefore,
Milica Gagic, E. Jamróz, S. Krizkova, Vedran Milosavljevic, Pavel Kopel, V. Adam   +5 more
semanticscholar   +1 more source