Results 91 to 100 of about 38,061 (191)

Pharmacological and neurophysiological aspects of space/motion sickness [PDF]

A motorized motion testing device modeled after a Ferris wheel was constructed to perform motion sickness tests on cats. Details of the testing are presented, and some of the topics covered include the following: xylazine-induced emesis; analysis of the ...
Crampton, George H., Lucot, James B.
core   +1 more source

Chronic regulation of colonic epithelial secretory function by activation of G protein-coupled receptors. [PDF]

, 2011
BACKGROUND: Enteric neurotransmitters that act at G protein-coupled receptors (GPCRs) are well known to acutely promote epithelial Cl(-) and fluid secretion.
Bertelsen, Lone S, Frankson, Michelle, Keely, Stephen J, Kelly, Orlaith B, Mroz, Magdalena S, Toumi, Ferial, Ward, Joseph B   +6 more
core   +1 more source

Alterations in histamine responses between juvenile and adult urinary bladder urothelium, lamina propria and detrusor tissues [PDF]

, 2020
Chess-Williams, Russ, Moro, Christian, Stromberga, Zane   +2 more
core   +1 more source

Calcium activates SK channels in the intact human lens. [PDF]

, 2003
Collison, DJ, Duncan, G, Rhodes, JD
core   +1 more source

Effects of Platelet-Activating Factor on Brain Microvascular Endothelial Cells. [PDF]

, 2018
Platelet-activating factor (PAF) is a potent phospholipid mediator that exerts various pathophysiological effects by interacting with a G protein-coupled receptor.
Abood, Mary E., Barlow, Christine L., Brailoiu, Eugen, Brailoiu, G. Cristina, Ramirez, Servio H.   +4 more
core   +1 more source

Structural basis of ligand recognition and design of antihistamines targeting histamine H4 receptor

Nature Communications
The histamine H4 receptor (H4R) plays key role in immune cell function and is a highly valued target for treating allergic and inflammatory diseases. However, structural information of H4R remains elusive.
Ruixue Xia, Shuang Shi, Zhenmei Xu, Henry F. Vischer, Albert D. Windhorst, Yu Qian, Yaning Duan, Jiale Liang, Kai Chen, Anqi Zhang, Changyou Guo, Rob Leurs, Yuanzheng He   +12 more
doaj   +1 more source

Integrating GPCR Regulation and Calcium Dynamics in Airway Smooth Muscle Function: A Comprehensive Review. [PDF]

Cells
Roy S, Gangipangi VK, Sharma P, Hancock RE, Sharma P.   +4 more
europepmc   +1 more source

Repurposing the antihistamine cyproheptadine for osteoarthritis: nothing to sneeze at. [PDF]

J Clin Invest
Loeser RF, Coryell PR.
europepmc   +1 more source

Protease-Activated Receptor 2 Activation Provokes an Increase in Intracellular Calcium and Serotonin Secretion in a Human Enteroendocrine Cell Line. [PDF]

Cell Biochem Funct
Pfanzagl B, Jensen-Jarolim E.
europepmc   +1 more source

G Protein-Coupled Receptors in Irritable Bowel Syndrome: Mechanisms and Therapeutic Opportunities. [PDF]

Int J Mol Sci
Zhu Z, Liu Z, He Y, He X, Zheng W, Jiang M.   +5 more
europepmc   +1 more source