Results 181 to 190 of about 467,605 (318)

Pathophysiological Mechanisms and Nonpharmacological Interventions in Irritable Bowel Syndrome: Current Insights and Future Directions

Journal of Nutrition and Metabolism, Volume 2026, Issue 1, 2026.
Irritable bowel syndrome, diagnosed using the ROME IV diagnostic criteria, is one of the most common dysfunctional disorders of the gastrointestinal system with a high global prevalence. Although symptom presentation is diverse, symptoms primarily manifest as abdominal pain, bloating, and alterations to bowel habits, negatively impacting quality of ...
Stefanie L. Y. Cheung, Leanne C. Kenway, Maharshi Bhaswant   +2 more
wiley   +1 more source

Protease-Activated Receptor 2 Activation Provokes an Increase in Intracellular Calcium and Serotonin Secretion in a Human Enteroendocrine Cell Line. [PDF]

Cell Biochem Funct
Pfanzagl B, Jensen-Jarolim E.
europepmc   +1 more source

Risks for human health related to the presence of plant lectins in food

EFSA Journal, Volume 24, Issue 1, January 2026.
Abstract The European Commission asked the European Food Safety Authority (EFSA) to assess the risk related to the presence of plant lectins in food. Based on the available evidence, the CONTAM Panel considered only phytohaemagglutinin (PHA), a legume lectin from beans (Phaseolus sp.), for the risk characterisation.
EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Agneta Åkesson, Vasileios Bampidis, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Gisela Degen, Antonio Hernández‐Jerez, Tim Hofer, Christer Hogstrand, Stefano Landi, Jean‐Charles Leblanc, Kyriaki Machera, Isabelle P. Oswald, Guido Rychen, Salomon Sand, Katharina Vejdovszky, Barbara Viviani, Hanne Frøkiær, Bettina Grasl‐Kraupp, Patrick Mulder, Pierre Rougé, Heather Wallace, Marios Georgiadis, José Ángel Gómez Ruiz, Eirini Kouloura, Olaf Mosbach‐Schulz, Lydia Alarcón Asensio, Eleni Gkimprixi, Evangelia Ntzani   +30 more
wiley   +1 more source

Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonists

, 2010
Sue Cramp, Hazel J. Dyke, Christopher Higgs, David E. Clark, Matthew Gill, Pascal Savy, Neil Jennings, Steve Price, Peter Lockey, Dennis Norman, Soraya S. Porres, Francis X. Wilson, Alison L Jones, Nigel G. Ramsden, Raffaella Mangano, Dan Leggate, Marie Andersson, Richard Hale   +17 more
openalex   +1 more source

G Protein-Coupled Receptors in Irritable Bowel Syndrome: Mechanisms and Therapeutic Opportunities. [PDF]

Int J Mol Sci
Zhu Z, Liu Z, He Y, He X, Zheng W, Jiang M.   +5 more
europepmc   +1 more source

Asthma in Patients With Confirmed Pulmonary Sarcoidosis [PDF]

Can Respir J
Pulmonary sarcoidosis and asthma can present identical symptoms, making clinical evaluation difficult if the two diseases overlap. Diagnostic challenges often lead to either overdiagnosis of asthma in patients with confirmed sarcoidosis or withholding appropriate asthma treatment.
Lewandowska A, Waśniowska D, Kołodziej M, Mirus-Arabik H, Gaczkowska A, Duszyńska O, Bułat K, Graczyk M, Rybacki C.   +8 more
europepmc   +2 more sources

Prodrug developments on histamine H3-receptors agonists

European Journal of Pharmaceutical Sciences, 1996
H. Stark, M. Krause, A. Rouleau, M. Garbagh, X. Ligneau, C. Mantion, P. Lavie, J.-M. Lecomte, J.-C. Schwartz, W. Schunack   +9 more
openaire   +1 more source

S 38093, a histamine H3 antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice [PDF]

, 2017
Jean‐Philippe Guilloux, Benjamin A. Samuels, Indira Mendez‐David, Alice Hu, Marjorie R. Levinstein, Charlène Faye, Maryam Mekiri, Elisabeth Mocaër, Alain M. Gardier, René Hen, Aurore Sors, Denis J. David   +11 more
openalex   +1 more source

Spatiotemporal calcium signaling patterns underlying opposing effects of histamine and TAS2R agonists in airway smooth muscle. [PDF]

Am J Physiol Lung Cell Mol Physiol
Conaway S, Richard J, Deshpande DA.
europepmc   +1 more source

Histamine 2 receptor-mediated immunomodulation in the mouse. I. Immunomodulation by the H2 agonist tolazoline.

, 1979
Johannes van Dijk, M Rapis, H. E. L. Jacobse-Geels, J M Willers   +3 more
openalex   +1 more source