Histamine H3 Receptor Heterogeneity in the Central Nervous System in Aging and Dementia. [PDF]
, 2011 The histamine H3R is a classic G-protein coupled receptor and is a potential therapeutic target for a number of central nervous system pathologies. Major pharmacological heterogeneity between and within species has hindered the clinical development of ...
LETHBRIDGE, NATASHA,LOUSIE
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Dualistic H1-mediated effect of histamine on the isolated human intestine
, 2005 Histamine (HA) contracts gastrointestinal smooth muscle cells from both animals and humans through the activation of H1 receptors. The recent discovery of the H4 receptor subtype, causing a rise in the intracellular Ca2+ levels and then representing a ...
POZZOLI, Cristina +6 more
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Papel dos receptores histaminérgicos da medula espinhal na inflamação articular de ratos e sua possível contribuição como adjuvante para os efeitos da morfina [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaA medula espinhal é conhecida por ser um centro de controle ortodrômico (nocicepção), bem como antidrômico ...
Silva, Taciane Stein da
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The effect of several α-adrenoceptor antagonists on the response to histamine in various tissues
, 1980 The effect of various α-receptor antagonists on the histamine-induced response of guinea pig ileum, guinea pig heart, and rabbit portal vein have been studied.
K. M. MacLeod +4 more
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Effect of histamine and histamine antagonists on natural and antibody-dependent cellular cytotoxicity of human lymphocytes in vitro [PDF]
, 1983 The in vitro effect of histamine and its antagonists, cimetidine and clemastine fumarate, on natural killer (NK) and antibody-dependent cellular Cytotoxicity (ADCC) activities of human lymphocytes was investigated.
Schwartz, Stanley A. +3 more
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Asymmetric synthesis and histamine receptor activity of new H1-receptor agonists and conformationally restricted H3-receptor antagonists [PDF]
, 2007 Histamine H1-Receptor (H1R) Ligands: Developing highly potent and selective histamine H1-receptor (H1R) agonists has been an arduous task for several decades.
Patil, Rameshwar
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Effects of histamine and histamine antagonists on hepatic bile flow in the conscious sheep
, 1984 1. The effects of histamine and histamine antagonists on bile flow have been studied using the cholecystectomized conscious sheep. Histamine stimulated bile flow in a dose-dependent manner (D50 = 15.7 μg/h per kg).
Lee, SP
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Pharmacologic characterization of a novel histamine receptor on human eosinophils.
, 1994 There is increased recognition that lung mast cell mediators not only produce the symptoms of acute asthma, but also result in the recruitment and activation of additional proinflammatory cells, such as eosinophils.
Kosinski, R +4 more
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Mouse P19 embryonal carcinoma cells express functional histamine H1-receptors
, 1993 In the present study, we have investigated the response in P19 embryonal carcinoma (EC) cells to histamine. We show that these cells, that resemble the pluripotent cells of an early mouse embryo, respond to histamine addition by a transient increase in ...
Leurs, R +6 more
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, 1986 The geometries of 14 histamine H1-receptor antagonists have been compared with the aim of finding out a common stereochemical vector of antihistaminic activity.
BERTOLASI, Valerio +2 more
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