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The Histamine H3 Receptor Antagonist DL77 Ameliorates MK801-Induced Memory Deficits in Rats. [PDF]

open access: yesFront Neurosci, 2018
Eissa N   +5 more
europepmc   +1 more source

Histamine H3 Receptor Agonists

Mini-Reviews in Medicinal Chemistry, 2004
The SAR of H3 ligands has been difficult to evaluate because of species differences, multiple isoforms and constitutive activity, among other complicating factors. A review is given of the sometimes-conflicting affinity, activity and efficacy data of H3 agonists that has been described in literature to date.
I J P, De Esch, K J, Belzar
openaire   +3 more sources

Molecular aspects of the histamine H3 receptor

Biochemical Pharmacology, 2007
The cloning of the histamine H(3) receptor (H(3)R) cDNA in 1999 by Lovenberg et al. [10] allowed detailed studies of its molecular aspects and indicated that the H(3)R can activate several signal transduction pathways including G(i/o)-dependent inhibition of adenylyl cyclase, activation of phospholipase A(2), Akt and the mitogen activated kinase as ...
Gerold, Bongers   +2 more
openaire   +2 more sources

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