Results 11 to 20 of about 13,967 (254)

Histamine H3 Receptor Ligands-KSK-59 and KSK-73-Reduce Body Weight Gain in a Rat Model of Excessive Eating. [PDF]

open access: goldPharmaceuticals (Basel), 2021
Mika K   +12 more
europepmc   +3 more sources

Activity-restoring mutations in the histamine H<sub>3</sub> receptor increase constitutive activity and reduce structural stability. [PDF]

open access: yesProtein Sci
Abstract The histamine H3 receptor (H3R) is a class A G protein‐coupled receptor (GPCR) that regulates neurotransmitter release in the central nervous system. Although structures of H3R in both inactive and active states have been elucidated, the functional roles of specific residues remain unclear.
Nakajima A   +6 more
europepmc   +2 more sources

Interaction of Central Glutamatergic and Histaminergic Systems on Food Intake Regulation in Layer Chickens [PDF]

open access: yesArchives of Razi Institute, 2021
This study purposed to discover the connection between the central glutamatergic and histaminergic systems on feeding behavior in layer chickens. In the first experiment, chicks obtained intracerebroventricular (ICV) injections of saline (control ...
M Mobarhan Fard   +3 more
doaj   +1 more source

Correlation of Histamine Receptors and Adrenergic Receptor in Broilers Appetite [PDF]

open access: yesArchives of Razi Institute, 2022
The current study was conducted to investigate the interaction between the central adrenergic and histaminergic systems and the broiler chick’s feed intake.
M Daneshvar   +3 more
doaj   +1 more source

Loss of Melanopsin Photoreception and Antagonism of the Histamine H3 Receptor by Ciproxifan Inhibit Light-Induced Sleep in Mice [PDF]

open access: yes, 2015
Light has direct effects on sleep and wakefulness causing arousal in diurnal animals and sleep in nocturnal animals. In the present study, we assessed the modulation of light-induced sleep by melanopsin and the histaminergic system by exposing mice to ...
Colas, Damien   +4 more
core   +14 more sources

Identification and characterization of ZEL-H16 as a novel agonist of the histamine H3 receptor. [PDF]

open access: yesPLoS ONE, 2012
The histamine H3 receptor (H3R) has been recognized as a promising target for the treatment of various central and peripheral nervous system diseases.
Ying Shi   +9 more
doaj   +1 more source

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