Results 81 to 90 of about 12,080 (218)
Narcolepsy initially misdiagnosed as schizophrenia: A case report
Sleep Research, EarlyView.
Feng Daoyi, Liu Xin, Xu Rui, He Lihua
wiley +1 more source
ABSTRACT Bronchopulmonary dysplasia (BPD) is a chronic lung disease primarily affecting preterm infants, characterised by impaired alveolar development and persistent inflammation, particularly associated with ventilator‐induced lung injury due to mechanical ventilation.
Lei Cao +4 more
wiley +1 more source
Histamine H3 receptor: A novel therapeutic target in alcohol dependence?
The brain histaminergic system is one of the diffuse modulatory neurotransmitter systems which regulate neuronal activity in many brain areas. Studies on both rats and mice indicate that histamine H3 receptor antagonists decrease alcohol drinking in ...
Pertti ePanula +3 more
doaj +1 more source
Increased brain histamine H3 receptor expression during hibernation in golden-mantled ground squirrels [PDF]
BACKGROUND: Hibernation is a state of extremely reduced physiological functions and a deep depression of CNS activity. We have previously shown that the histamine levels increase in the brain during hibernation, as does the ratio between histamine and ...
Anichtchik, OV +4 more
core +4 more sources
Restless Legs Syndrome Associated With Fexofenadine Use: A Case Report
Flowchart of possible fexofenadine‐induced RLS pathophysiology. ABSTRACT Restless legs syndrome (RLS) is a neurological sensorimotor disorder characterized by an irresistible urge to move the legs, typically worsening at night and leading to sleep disturbance.
Abdulrahman M. Albeshry
wiley +1 more source
Anticonvulsive effect of nonimidazole histamine H3 receptor antagonists
To determine the potential of histamine H3 receptor (H3R) ligands as new antiepileptic drugs (AEDs), aromatic ether, and diether derivatives (1-12) belonging to the nonimidazole class of ligands, with high in-vitro binding affinity at human H3R, were tested for their in-vivo anticonvulsive activity in the maximal electroshock (MES)-induced and ...
Sadek, Bassem +7 more
openaire +3 more sources
This study provides a novel framework modeling neurodevelopment in self‐limited epilepsy with centrotemporal spikes. We identify eight biologically interpretable brain structural deviation patterns, which are linked to clinical phenotypes and molecular profiles involving cognition and mitochondrial function. This integration elucidates multidimensional
Siqi Yang +6 more
wiley +1 more source
The conserved sequences of the mouse histamine H3 receptor at the potential alternative splice junctions suggest that the splice isoforms found in guinea pig, rat, human, and hamster may also be present in the mouse.
Wenyong Ding +3 more
doaj +1 more source
The evolving small-molecule fluorescent-conjugate toolbox for Class A GPCRs [PDF]
The past decade has witnessed fluorescently tagged drug molecules gaining significant attraction in their use as pharmacological tools with which to visualize and interrogate receptor targets at the single-cell level.
Hill, Stephen J. +2 more
core +2 more sources
Microbial metabolites in tumor epigenetic regulation
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang +31 more
wiley +1 more source

