Results 111 to 120 of about 10,224 (203)

Antagonism of Histamine H3 receptors Alleviates Pentylenetetrazole-Induced Kindling and Associated Memory Deficits by Mitigating Oxidative Stress, Central Neurotransmitters, and c-Fos Protein Expression in Rats. [PDF]

Molecules, 2020
Alachkar A, Azimullah S, Lotfy M, Adeghate E, Ojha SK, Beiram R, Łażewska D, Kieć-Kononowicz K, Sadek B.   +8 more
europepmc   +1 more source

Non-imidazole-based histamine H3 receptor antagonists with anticonvulsant activity in different seizure models in male adult rats

Drug Design, Development and Therapy, 2016
Bassem Sadek,1 Ali Saad,1 Gniewomir Latacz,2 Kamil Kuder,2 Agnieszka Olejarz,2 Tadeusz Karcz,2 Holger Stark,3 Katarzyna Kieć-Kononowicz2 1Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, United Arab Emirates ...
Sadek B, Saad A, Latacz G, Kuder K, Olejarz A, Karcz T, Stark H, Kiec´-Kononowicz K   +7 more
doaj  

Structure-activity studies with histamine H3-receptor ligands.

Journal de pharmacie de Belgique, 1995
Analogues of thioperamide have been synthesised and tested in vitro on rat cerebral cortex to explore structure-activity relationships with the intention of designing compounds which do not possess the thiourea group of thioperamide and which may have improved brain penetration.
Ganellin, C. R., Fkyerat, A., Hosseini, S. K., Khalaf, Y. S., Piripitsi, A., Tertiuk, W., Arrang, J. M., Garbarg, M., Ligneau, X., Schwartz, J. C.   +9 more
openaire   +2 more sources

Histamine H3 receptors in the paraventricular thalamus link sleep loss to fat overconsumption

Cell Reports
Summary: Sleep loss promotes obesity, yet the neural mechanisms linking disrupted sleep patterns to abnormal feeding behaviors remain unclear. By integrating the UK Biobank cohort analyses with mouse sleep restriction (SR) models, we demonstrate that ...
Xinyue Zhao, Yuting Yan, Jingjia Liang, Yuanjie Zhang, Menghan Li, Zhuchen Zhou, Mengting Liu, Wenkai Lin, Li Cheng, Yi Wang, Cenglin Xu, Lingyu Xu, Zhong Chen, Yanrong Zheng   +13 more
doaj   +1 more source

Histamine H3 receptor inverse agonists/antagonists influence intra-regional cortical activity and inter-regional synchronization during resting state: an exploratory cortex-wide imaging study in mice

Molecular Brain
The histaminergic system plays a key role in modulating learning and memory, wakefulness, and energy balance. Histamine H3 receptors constitutively inhibit the synthesis and release of histamine and other neurotransmitters. Therefore, H3 receptor inverse
Sentaro Kaita, Yoshikazu Morishita, Kenta Kobayashi, Hiroshi Nomura   +3 more
doaj   +1 more source

Carotid body plastic behavior: evidence for D2–H3 receptor–receptor interactions

Frontiers in Physiology
Dopamine and histamine receptors D2R and H3R are G protein-coupled receptors (GPCRs) which can establish physical receptor–receptor interactions (RRIs), leading to homo/hetero-complexes in a dynamic equilibrium.
Elena Stocco, Elena Stocco, Elena Stocco, Aron Emmi, Maria Martina Sfriso, Aleksandar Tushevski, Raffaele De Caro, Veronica Macchi, Andrea Porzionato   +8 more
doaj   +1 more source

Fishing for histamine H3 receptor functions [PDF]

Acta Physiologica, 2017
openaire   +2 more sources

Histamine H3 receptor [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

Reproductive and fetal toxicity studies of histamine H3 receptor antagonist DL76 used in mice to prevent maximal electroshock-induced seizure

Frontiers in Pharmacology
Introduction: Brain histamine is considered an endogenous anticonvulsant and histamine H1 receptor. H1R antagonists have, in earlier studies, been found to induce convulsions.
Salim M. Bastaki, Salim M. Bastaki, Yousef M. Abdulrazzaq, Marwan Abdelrahim Zidan, Mohamed Shafiullah, Mohamed Shafiullah, Saif Ghdayer Alaryani, Fatima Awad Alnuaimi, Ernest Adeghate, Sahar Mohsin, Amal Akour, Agata Siwek, Dorota Łażewska, Katarzyna Kieć-Kononowicz, Bassem Sadek, Bassem Sadek   +15 more
doaj   +1 more source

Histamine H3 receptor (HRH3) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source