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Histamine H3-Receptor Inverse Agonists as Novel Antipsychotics
Central Nervous System Agents in Medicinal Chemistry, 2009Schizophrenia (SZ) that is resistant to treatment with dopamine (DA) D2 antagonists may involve changes other than those in the dopaminergic system. Recently, histamine (HA), which regulates arousal and cognitive functions, has been suggested to act as a neurotransmitter in the central nervous system.
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H3 Receptor Miniseries: The histamine H3 receptor and eating behavior
2011Interest in the histaminergic system as a potential target for the treatment of feeding disorders is driven by the unsatisfactory history of the pharmacotherapy of obesity. Eating behavior is regulated by a complex interplay of central neurotransmitter systems, peripheral endocrine stimuli, the circadian rhythm, and environmental cues, all factors that
PASSANI, MARIA BEATRICE +2 more
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Stress and brain H3-histamine receptors
Inflammation Research, 1995P, Ghi +3 more
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Histamine H3 receptors and gastric acid secretion
Gastroenterology, 1998CORUZZI, Gabriella, BERTACCINI G.
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Medicinal chemistry of histamine H3 receptor antagonists
1998Publisher Summary This chapter discusses medicinal chemistry of histamine H3 receptor antagonists and provides an update on the recent progress being made. Several improved clinical candidates have emerged and are progressing towards human clinical trials.
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Histamine H3 receptors and the gastrointestinal tract
Drug Discovery Today, 1999openaire +2 more sources
Histamine H3- Receptor Agonists and Antagonists
2008Holger Stark, Walter Schunack
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Histamine H3 receptor (HRH3); norepinephrine transporter
Science-Business eXchange, 2010openaire +1 more source