Results 311 to 320 of about 98,227 (378)

Bacterial Histamine as a Therapeutic Target for Abdominal Pain in Irritable Bowel Syndrome: A Literature Review. [PDF]

Cureus
Mohamed Siraj H, Usaid M, Shaikh S, Dalain M, Ansari Y, Zehra Naqvi S, Hossain R, Anum H, Andrews Ravi C, Pant N, Awasarikar M, Husain K, Anand Hanchate A, Sagam A, Balasubramanian A.   +14 more
europepmc   +1 more source

Hybrid Molecules as Efficient Drugs against Multidrug‐Resistant Malaria Parasites

ChemMedChem, Volume 20, Issue 11, June 2, 2025.
Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Anne Robert, Lucie Paloque, Jean‐Michel Augereau, Flore Nardella, Michel Nguyen, Bernard Meunier, Françoise Benoit‐Vical   +6 more
wiley   +1 more source

Subtype-specific dysregulation of biogenic amine-related genes and miRNAs in breast cancer: identification of DRD2, HRH2, and HRH4 as potential therapeutic targets in TNBC and HER2+ subtypes. [PDF]

Breast Cancer Res Treat
Sirek A, Sirek T, Nowakowski R, Borawski P, Ossowski P, Mitka-Krysiak K, Zmarzły N, Boroń K, Chalcarz M, Kuraszewska B, Szulik M, Boroń D, Grabarek BO.   +12 more
europepmc   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, Volume 19, Issue 6, Page 1737-1750, June 2025.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

Intranasal Chlorpheniramine for Early Symptomatic Treatment of COVID-19 and the Impact on Long-COVID. [PDF]

Cureus
Ferrer G, Valerio-Pascua F, Alas-Pineda C, Gaitán-Zambrano K, Pavón-Varela DJ.   +4 more
europepmc   +1 more source

Histamine 2 receptor: Emerging target for the treatment of attention-deficit/hyperactivity disorder. [PDF]

Cell Rep Med
Shan L, Swaab DF.
europepmc   +1 more source

Histamine and TH2 cytokines regulate the biosynthesis of cysteinyl-leukotrienes and expression of their receptors in human mast cells. [PDF]

Inflamm Res
Gehlhaar P, Schaper-Gerhardt K, Gutzmer R, Hasler F, Röhn TA, Werfel T, Mommert S.   +6 more
europepmc   +1 more source

Modafinil Ameliorated Fibromyalgia Syndrome in Rats by Modulating Mast Cells and Microglia Activation Through Dopamine/Substance P/MRGPRX/Histamine and PI3K/p-Akt/NF-κB Signaling Pathways. [PDF]

J Neuroimmune Pharmacol
Kamal MM, Essam RM, Abdelkader NF, Zaki HF.   +3 more
europepmc   +1 more source

Histamine Modulation of the Basal Ganglia Circuitry in the Motor Symptoms of Parkinson's Disease. [PDF]

CNS Neurosci Ther
Zhu HX, Lou WW, Jiang YM, Ciobanu A, Fang CX, Liu CY, Yang YL, Cao JY, Shan L, Zhuang QX.   +9 more
europepmc   +1 more source

Deciphering Histamine Pathway Networks in the Human Brain: A Multimodal Approach to Cognition and Psychiatric Disorders

Martins D, Veronese M, Wamelen Dv, Shan L, Howes O, Hampshire A, Turkheimer F, Williams SC.   +7 more
europepmc   +1 more source