What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Xue Tang +5 more
wiley +1 more source
A rare case of extra nodal Rosai-Dorfman disease with isolated multifocal osseous manifestation
Sinus histiocytosis with massive lymphadenopathy (SHML) or Rosai-Dorfman disease is a non-neoplastic condition which typically presents as massive, bilateral cervical lymphadenopathy and can involve multiple extranodal organ systems such as skin, eyes ...
Maharshi H Patel +3 more
doaj +1 more source
Emperipolesis in a Case of Adult T Cell Lymphoblastic Lymphoma (Mediastinal type)-Detected at FNAC and Imprint Cytology [PDF]
Emperipolesis is a condition in which viable hematopoetic cells are seen intact in the cytoplasm of host cell without damage. This phenomenon is seen in many physiologic and pathologic conditions, its presence in Rosai Dorfman disease (RDD) is ...
Abhishekh, MG +3 more
core
Interstitial granulomatous dermatitis due to borreliosis [PDF]
3Interstitial granulomatous dermatitis (IGD) is a rare dermatosis of unknown cause with characteristic histopathological features and variable clinical expression.
Di Meo, Nicola +2 more
core +3 more sources
Histopathological Aspects of Common Immune Checkpoint Inhibitors Induced Skin Toxicities
ABSTRACT Background The histological characteristics of checkpoint inhibitors‐related adverse events (cirAEs) are not well studied and there are conflicting data regarding their similarities and differences with their idiopathic counterparts. Objectives To investigate the histological characteristics of the most common cirAEs.
Christina Kemanetzi +12 more
wiley +1 more source
Assessment of antigen presenting cell infiltration in lung tissues of patients with bronchiectasis
Background: Bronchiectasis is a chronic disease characterized by permanent dilatation of the conducting airways accompanied by sustained inflammation. Aims: To assess whether chronic inflammation of lungs in bronchiectasis is associated with alterations ...
Waseem M Hajjar +5 more
doaj +1 more source
Extreme Peripheral Blood Plasmacytosis Mimicking Plasma Cell Leukemia as a Presenting Feature of Angioimmunoblastic T-Cell Lymphoma (AITL). [PDF]
Angioimmunoblastic T-cell lymphoma (AITL) is one of four major subtypes of nodal peripheral T cell lymphoma, characterized by its cell of origin, the follicular helper T-cell (TFH).
Alpdogan, Onder +7 more
core +1 more source
Nodular lymphocyte predominant hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma : endpoints of a spectrum of one disease? [PDF]
In contrast to the commonly indolent clinical behavior of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), T cell/histiocyte rich large B cell lymphoma (THRLBCL) is frequently diagnosed in advanced clinical stages and has a poor prognosis ...
Döring, Claudia +13 more
core +3 more sources
Successful Treatment of Paediatric Necrobiosis Lipoidica With Baricitinib
ABSTRACT Necrobiosis lipoidica (NL) is a rare, chronic granulomatous condition that typically presents as sharply demarcated plaques with telangiectasia and atrophic centres. Paediatric cases are uncommon, and treatment options often fail to address refractory cases.
P. Simões Farinha, M. J. Paiva‐Lopes
wiley +1 more source
Extra Nodal (Cutaneous) Rosai Dorfman Disease
Rosai-Dorfman disease is an extremely rare disorder characterized by proliferation and accumulation of histiocytes in lymph nodes, usually in the cervical region. In approximately 43% cases, this accumulation occurs in extra nodal sites such as the skin,
Talha Ahmed +5 more
doaj

