Hemophagocytic Histiocytic Sarcoma in Dog [PDF]
Background: Histiocytic sarcoma can present in a localized or disseminated form, being a malignant neoplasm derived from interstitial dendritic cells. Another form of the disease is called hemophagocytic histiocystic sarcoma (HHS), which originates from macrophages located in the splenic red pulp and bone marrow.
Goulart, Juliana das Chagas+5 more
openaire +5 more sources
Primary histiocytic sarcoma in the brain with renal metastasis causing internal ophthalmoparesis and external ophthalmoplegia in a Maine Coon cat [PDF]
Case summary An 11-year-old neutered male Maine Coon cat was presented for investigation of anisocoria and depression. Neurological examination was consistent with a lesion at the level of the middle cranial fossa, and biochemistry was indicative of ...
Susana Monteiro+3 more
doaj +3 more sources
Gene expression profiling of histiocytic sarcomas in a canine model: the predisposed flatcoated retriever dog. [PDF]
BackgroundThe determination of altered expression of genes in specific tumor types and their effect upon cellular processes may create insight in tumorigenesis and help to design better treatments.
Kim M Boerkamp+9 more
doaj +3 more sources
Invasive nasal histiocytic sarcoma as a cause of epilepsy [PDF]
Case summary A 10-year-old neutered female domestic shorthair cat was presented with an acute onset of neurological signs suggestive of a right-sided forebrain lesion, temporal lobe epilepsy and generalised seizure activity.
Koen M Santifort+5 more
doaj +2 more sources
Fas-ligand and caspase-3 positivity in three cases of histiocytic sarcoma: a different etiopathogenic pathway? [PDF]
Histiocytic sarcoma (HS) is a rare malignant neoplasia of hematopoietic origin and unknown etiology. We studied three patients with histiocytic sarcoma reviewing the morphological and immunohistochemical aspects.
Cristiano Claudino Oliveira+2 more
doaj +3 more sources
Fine needle aspiration of Histiocytic sarcoma
Histiocytic sarcoma is derived from histiocytes and is among the rarest of the tumors affecting the lymphoid tissue. We report a case of a histiocytic sarcoma arising from the lymph node in a 35-year-old male who came for a fine needle aspiration ...
Varuna Mallya+2 more
doaj +3 more sources
Histiocytic sarcoma involving multiple abdominal sites: A rare case with KRAS mutation and response to ICE chemotherapy [PDF]
Histiocytic sarcoma (HS) is a rare and aggressive malignant neoplasm from histiocytic cells. This case report describes a 52-year-old male with HS involving multiple abdominal sites, diagnosed through imaging, histopathology, and immunohistochemical ...
Shahad Khalid Hussein Hussein, MD+1 more
doaj +2 more sources
An 8-year-old girl with secondary histiocytic sarcoma with BRAFV600 mutation following T-cell acute lymphoblastic leukemia demonstrating stable disease for 3 years on dabrafenib and trametinib – a case report and literature review [PDF]
Background Histiocytic sarcoma as a secondary malignancy following childhood leukemia is extremely uncommon with fewer than 20 cases reported worldwide. They often pose a diagnostic challenge and prognosis is dismal.
Sue Lyn Tan+3 more
doaj +2 more sources
Multifocal histiocytic sarcoma of the gastrointestinal tract
We report a rare case of extranodal histiocytic sarcoma with multifocal gastrointestinal tract involvement, which has not been documented in the literature so far.
Shirley Sundersingh+3 more
doaj +3 more sources
Primary pulmonary histiocytic sarcoma with high PD‐L1 expression benefited from immunotherapy: A case report and bioinformatic analysis [PDF]
Histiocytic sarcoma is an aggressive haematopoietic malignancy accounting for less than 1% of haematolymphoid neoplasms with a diagnosis based on morphology and immunophenotype of tissue biopsies with a very poor prognosis.
Yuanjie Lin+3 more
doaj +2 more sources