Results 81 to 90 of about 5,123 (202)

The Clinicopathologic Spectrum of Rosai–Dorfman–Destombes Disease in Adults: An Analysis of 16 Cases

European Journal of Haematology, EarlyView.
ABSTRACT Rosai–Dorfman–Destombes disease (RDD) is a rare histiocytic proliferation with protean clinical manifestations, resulting from the accumulation of activated histiocytes within nodal and extra‐nodal tissues. The diagnosis can be missed, particularly when biopsies are obtained from extra‐nodal sites, where histological features may be less ...
Mark Trinder, Collin Pryma, Emily Leung, Graham W. Slack, Pedro Farinha, Sean Young, Neval Ozkaya, Mollie Carruthers, Luke Y. C. Chen   +8 more
wiley   +1 more source

Caregiver burden in owners of dogs and cats undergoing anticancer therapy in a referral hospital in Hong Kong

Journal of Small Animal Practice, EarlyView.
Objectives To assess the prevalence and factors associated with increased caregiver burden among owners of dogs and cats undergoing anti‐cancer therapy in Hong Kong. Materials and Methods Clients of the oncology service of a large veterinary hospital in Hong Kong completed an online survey during real‐time consultations.
K. M. Tam, A. Giuliano, S. S. U. H. Bukhari, P. V. Steagall   +3 more
wiley   +1 more source

Multi-omics approach identifies germline regulatory variants associated with hematopoietic malignancies in retriever dog breeds.

PLoS Genetics, 2021
Histiocytic sarcoma is an aggressive hematopoietic malignancy of mature tissue histiocytes with a poorly understood etiology in humans. A histologically and clinically similar counterpart affects flat-coated retrievers (FCRs) at unusually high frequency,
Jacquelyn M Evans, Heidi G Parker, Gerard R Rutteman, Jocelyn Plassais, Guy C M Grinwis, Alexander C Harris, Susan E Lana, Elaine A Ostrander   +7 more
doaj   +1 more source

Malignização primária no tumor de células gigantes: um estudo de caso [PDF]

, 2009
CONTEXT: Primary malignancy in giant cell tumor (PMGCT) is rare. It is defined as a high-grade sarcoma originating in a giant cell tumor (GCT) and seems to behave less aggressively than its secondary counterpart does.
BAPTISTA, André Mathias, BISPO JÚNIOR, Rosalvo Zósimo, BRUNO, José Marcello, CAMARGO, Olavo Pires de, IDA, Cristiane Marie, OLIVEIRA, Cláudia Regina Gomes Cardim Mendes de, RIBEIRO, Marcelo Barbosa   +6 more
core   +1 more source

Advancements in genetic analysis: Insights from a case study and review of next‐generation sequencing techniques for veterinary oncology applications

Veterinary Clinical Pathology, EarlyView.
Abstract Acute myeloid leukemia (AML) poses significant challenges in veterinary medicine, with limited treatment options and poor survival rates. While substantial progress has been made in characterizing human AML, translating these advancements to veterinary practice has been hindered by limited molecular understanding and diagnostic tools. The case
R. Adam Harris, Jillian Nolan, Dylan Ammons, Samantha Beeson, Douglas Thamm, Anne Avery   +5 more
wiley   +1 more source

Histiocytic sarcoma in dogs: epidemiology, anatomopathology, and immunohistochemistry [PDF]

Pesquisa Veterinária Brasileira
: Histiocytic sarcomas have been described in veterinary medicine since 1980, but studies on the subject are still scarce. Based on this, the objective of this article is to describe the epidemiological, anatomopathological and immunohistochemical ...
Flávia S. Da Luz, Renata D. Mazaro, Gabriela Hartmann, Tereza Cristina Da Silva, Bruno Cogliati, Lilian R. Marques de Sá, Glaucia D. Kommers, Alexandre A. Tonin, Rafael A. Fighera   +8 more
doaj   +1 more source

Genomic profiling of primary histiocytic sarcoma reveals two molecular subgroups

Haematologica, 2020
Histiocytic sarcoma is a rare malignant neoplasm that may occur de novo or in the context of a previous hematologic malignancy or mediastinal germ cell tumor.
Caoimhe Egan, Alina Nicolae, Justin Lack, Hye-Jung Chung, Shannon Skarshaug, Thu Anh Pham, Winnifred Navarro, Zied Abdullaev, Nadine S. Aguilera, Liqiang Xi, Svetlana Pack, Stefania Pittaluga, Elaine S. Jaffe, Mark Raffeld   +13 more
doaj   +1 more source

A Genome Assembly-Integrated Dog 1 Mb BAC Microarray: A Cytogenetic Resource for Canine Cancer Studies and Comparative Genomic Analysis [PDF]

, 2010
Molecular cytogenetic studies have been instrumental in defining the nature of numerical and structural chromosome changes in human cancers, but their significance remains to be fully understood.
Breen, M., Duke, S. E., Ellis, P., Evans, A., Karlsson, Elinor Kathryn, Langford, C.F., Lindblad-Toh, K., Thomas, R.   +7 more
core   +3 more sources

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Influence of Pretreatment Polarographically Measured Oxygenation Levels in Spontaneous Canine Tumors Treated with Radiation Therapy [PDF]

, 2018
Background and Purpose:: The level of hypoxia in primary tumors has been described to influence response to treatment. The aim of the present study was to investigate the impact of pretreatment oxygen level measurements in spontaneous canine tumors on ...
Achermann, Roger, Kaser-Hotz, Barbara, Ohlerth, Stefanie, Rohrer Bley, Carla, Roos, Malgorzata, Wergin, Melanie   +5 more
core