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Differentiation of Langerhans cells in Langerhans cell histiocytosis
Blood, 2001Langerhans cell histiocytosis (LCH) consists of lesions composed of cells with a dendritic Langerhans cell (LC) phenotype. The clinical course of LCH ranges from spontaneous resolution to a chronic and sometimes lethal disease. We studied 25 patients with various clinical forms of the disease.
F, Geissmann +8 more
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Langerhans cell histiocytosis and dermatophytosis
Journal of the American Academy of Dermatology, 1993Langerhans cell histiocytosis (LCH) is regarded as a disorder of histiocytic cell proliferation of the Langerhans type, probably resulting from altered immunoregulation. Cutaneous involvement is frequent and often appears as a scaling papular eruption that resembles seborrheic dermatitis; when limited to the scalp, scaling and erythema may also be ...
A S, Pakula, A S, Paller
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LANGERHANS CELL HISTIOCYTOSIS OF THE SKIN
Hematology/Oncology Clinics of North America, 1998Cutaneous involvement in Langerhans cell histiocytosis (LCH) occurs in 50% of cases and may be the presenting feature. It is, therefore, important to recognize the wide spectrum of clinical disease that this disorder may adopt in the skin. Cutaneous involvement is not necessarily a benign feature and many patients progress to multi-system disease ...
S, Munn, A C, Chu
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Langerhans cell histiocytosis with disequilibrium
Auris Nasus Larynx, 2012Langerhans cell histiocytosis (LCH) is a very rare disease in which granulation tissue forms in various organs and the central nervous system (CNS) due to monoclonal proliferation of Langerhans cells. Some patients develop ataxia, tremor, or neurodegenerative abnormalities (such as personality changes and mental deterioration) several years after the ...
Tomoe, Nakamura +6 more
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Langerhans Cell Histiocytosis of the Orbit
European Journal of Ophthalmology, 2013Purpose The management of Langerhans cell histiocytosis is controversial. This study evaluated our clinical experience and therapeutic results in orbital Langerhans cell histiocytosis. Methods This is a retrospective, noncomparative interventional case series involving 17 consecutive patients with biopsy-proven orbital Langerhans cell histiocytosis ...
Hayyam, Kiratli +2 more
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Pulmonary Langerhans’ cell histiocytosis
2007Pulmonary Langerhans’ cell histiocytosis (PLCH) is a diffuse, smoking-related lung disease characterized pathologically by bronchiolocentric inflammation, cyst formation, widespread vascular ...
Harari S., Caminati A.
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Langerhans’ cell histiocytosis in adults
Journal of the American Academy of Dermatology, 1997Three cases of Langerhans' cell histiocytosis with unusual clinical and histopathologic features are described. The first two cases illustrate diagnostic pitfalls that underscore the importance of considering Langerhans' cell histiocytosis in the differential diagnosis of purpuric papular eruptions of the scalp and intertriginous areas, particularly in
R, Mejia +5 more
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Langerhans cell histiocytosis of the larynx
International Journal of Pediatric Otorhinolaryngology, 2000A pediatric case of Langerhans cell histiocytosis leading to severe and recurrent subglottic stenosis, ultimately necessitating partial cricotracheal resection, is presented and the literature on this very rare disorder is briefly reviewed.
M L, Duynstee +3 more
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LANGERHANS CELL HISTIOCYTOSIS IN ADULTS
Hematology/Oncology Clinics of North America, 1998Langerhans cell histiocytosis in the adult is rare, but it is important to recognize its occurrence, as it must be differentiated from lymphoma, myeloma, and a variety of skin conditions and endocrinopathies. It has been reported in patients up to the ninth decade of life, and occurs equally in men and women.
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