Results 41 to 50 of about 42,023 (285)

Effective BRAF inhibitor vemurafenib therapy in a 2-year-old patient with sequentially diagnosed Langerhans cell histocytosis and Erdheim-Chester disease [PDF]

, 2017
Erdheim–Chester disease (ECD) is a rare histiocytic disorder, characterized by the xanthomatous infiltration of tissues by CD68-positive and CD1a-/CD100-negative foamy histiocytes. In childhood, ECD is exceptionally rare, and only a dozen cases have been
Bánusz, Rita, Csomor, Judit, Csóka, Monika, Kertész, Gabriella, Krisztián Kállay, Varga, Edit, Váradi, Zsófia   +6 more
core   +2 more sources

Clinicopathological characteristics, prognostic factors, and outcomes of elderly patients with lymphoma‐associated hemophagocytic lymphohistiocytosis: A multicenter analysis

Cancer Medicine
Background Lymphoma is the most common secondary cause of hemophagocytic lymphohistiocytosis (HLH) in adults. Lymphoma‐associated HLH (LA‐HLH) in the elderly population is not rare, however, little has been reported regarding clinicopathological ...
Yi Miao, Jing Zhang, Xuzhang Lu, Meng Wu, Bingzong Li, Liang Yu, Miao Sun, Yun Zhuang, Yuqing Miao, Haiwen Ni, Xiaoyan Xie, Jingyan Xu, Yunping Zhang, Min Zhao, Min Xu, Wanchuan Zhuang, Weiying Gu, Guoqiang Lin, Haiying Hua, Jianfeng Zhu, Maozhong Xu, Tao Jia, Ping Liu, Lijia Zhai, Tongtong Zhang, Qiurong Shan, Qiudan Shen, Jun Qian, Chunling Wang, Jianyong Li, Wenyu Shi   +30 more
doaj   +1 more source

A Case of Multisystemic Langerhans Cell Histiocytosis in an Adult

Proceedings of Singapore Healthcare, 2011
Langerhans cell histiocytosis is a rare disease in adults with a myriad of clinical presentations. A case of multisystemic Langerhans cell histiocytosis with involvement of bone, skin, lungs, and the hypothalamic-pituitary-axis is reported.
Chiaw Ling Chng MBBS, MRCP
doaj   +1 more source

Bilateral breast Rosai‐Dorfman disease screen detected by mammography

Clinical Case Reports, 2023
Rosai‐Dorfman disease (RDD) is a proliferative disorder of histiocytes typically found in nodal sites and commonly observed in females. Patients often present with systemic symptoms such as fever, lymphadenopathy, and weight loss.
Christina Sumner, Karma Salem, Luma Abunimer, Abdulwahab Ewaz, Linsheng Zhang, Ashley Monsrud, Nabil Calisi   +6 more
doaj   +1 more source

An unusual case of intertrigo in an adult caused by purely cutaneous Langerhans cell histiocytosis [PDF]

, 2016
We report a case of persistent intertrigo in an adult, eventually diagnosed as cutaneous Langerhans cell histiocytosis (LCH). It is known that LCH has a predilection for intertriginous areas, however purely cutaneous disease as in our case, is uncommon ...
Baldacchino, Godfrey, Betts, Alexandra, Boffa, Michael J., Gatt, Alex   +3 more
core  

Growth of children with Langerhans cell histiocytosis [PDF]

, 1995
Conclusion: GH deficiency is not a common manifestation of LCH in childhood and GH provocation tests are only indicated when there is a poor or decelerating growth rate.
Egeler, R.M. (Maarten), Hoek, A.C.J. (A. C J) van den, Hählen, K. (Karel), Karstens, A. (A.)   +3 more
core   +1 more source

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan, Yunhui Wu, Feng Liu, Heng Fu, Yaqi Meng, Yingwei Ou, Xijing Yuan, Ian M. Adcock, Man Jia, Xiaoning Zeng, Xin Yao   +10 more
wiley   +1 more source

HYSTYOCYTOSIS X: VERIFICATION OF DIAGNOSIS

Vestnik Dermatologii i Venerologii, 2018
A clinical case of histiocytosis X, rarely found in the practice of a dermatovenereologist, is described, the pathognomonic clinical symptoms of this dermatosis, including skin lesions, that occur in 50 to 80 % of cases of all forms are displayed.
V. V. Starostenko, L. A. Anisimova, O. A. Sidorenko, E. P. Opruzhenkova   +3 more
doaj   +1 more source

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

Histiocytosis x: Recurrent isolated mandibular lesion (case report) [PDF]

, 2003
Histiocytosis X usually affects children and adolescents. In our case, a 54-year-old woman was admitted to hospital for evaluating and treatment of an isolated, painless swelling of the left side of the mandible.
Arizanović Marko, Basta-Jovanović Gordana M., Jovanović Milena, Stefanović Predrag   +3 more
core   +1 more source