Results 71 to 80 of about 56,324 (305)
Primary oral manifestation of Langerhans cell histiocytosis refractory to conventional therapy but susceptible to BRAF-specific treatment: a case report and review of the literature [PDF]
, 2019 Langerhans cell histiocytosis (LCH) is a diagnostic and therapeutic challenge. We report on a rare case of its primary oral manifestation that was treated successfully with the BRAF-specific agent, vemurafenib, after insufficient standard LCH treatment ...
Beck-Broichsitter, Benedicta +8 more
core +1 more source
Lamotrigine and anti‐seizure medications in HLH: A systematic review
British Journal of Haematology, EarlyView.Lamotrigine and other anti‐seizure medications have been reported to cause both haemophagocytic lympho‐histiocytosis (HLH) and drug‐induced hypersensitivity syndrome (DIHS). HLH and DIHS have many characteristic clinical, laboratory, pathological findings and underlying mechanisms; we identified significant clinical overlap between these two syndromes ...
Yaswanta K. Gummadi +4 more
wiley +1 more source
Journal of Oral Medicine and Oral Surgery, 2022 Introduction: Langerhans cell histiocytosis (LCH) is an abnormal clonal proliferation of Langerhans cells secondary to immune process, mutation of oncogene or genetic predispositions. It preferentially affects bone, lung and skin.
Morcel Marion +5 more
doaj +1 more source
Clinical Endocrinology, EarlyView.ABSTRACT Objective This study investigated the prevalence, characteristics, and endocrine implications of thyroid incidentalomas detected during lymphoma staging using FDG‐PET/CT. Design Retrospective cohort study. Patients A total of 795 adult patients with lymphoma who underwent FDG‐PET/CT for staging at a tertiary oncology centre were included ...
Marcos Tadashi Kakitani Toyoshima +10 more
wiley +1 more source
A Case of Orbital Langerhans Cell Histiocytosis in an Adult
Acta Médica Portuguesa, 2019 Langerhans cell histiocytosis remains an enigmatic disease with a very heterogeneous presentation. We describe a rare case of orbital Langerhans cell histiocytosis in a 39-year-old female patient who presented right orbital pain and edema of the upper ...
Inês Carneiro +2 more
doaj +1 more source
Paraneoplastic cerebellar degeneration associated with lymphoepithelial carcinoma of the tonsil [PDF]
, 2013 Background: Paraneoplastic cerebellar degeneration (PCD) is a classical tumor-associated, immune-mediated disease typically associated with gynecological malignancies, small-cell lung-cancer or lymphoma.
Hartmann, Sylvia +5 more
core +1 more source
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Langerhans cell sarcoma (LCS) is a rare neoplastic proliferation of Langerhans cell with aggressive clinical behavior and involves multiple organ systems, including the skin. LCS is characterized by marked cytologic atypia, frequent mitoses including atypical ones, and expression of CD1a, S100, and langerin (CD207).
Randa Obid +8 more
wiley +1 more source
Rosai‐Dorfman disease presenting with solitary liver mass without lymphadenopathy: A case report
Clinical Case Reports, 2021 Rosai‐Dorfman disease (RDD), as a lymphoproliferative disorder with unknown etiology, is commonly identified with systemic clinical manifestations in various organs. In this case study, RDD occurrence was reported with an exceedingly liver mass.
Yousef Roosta +9 more
doaj +1 more source
Sinus Histiocytosis: An Uncommon Presentation of an Uncommon Condition [PDF]
, 2015 Introduction Rosai–Dorfman Disease (RDD), also known as Sinus Histiocytosis with Massive Lymphadenopathy (SHML), is a rare, benign, proliferative disorder of macrophages and monocytes that was first described by Rosai and Dorfman in 1969.
Greco, MD, Allison, Kane, MD, Gregory
core +2 more sources
Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis.
Blood, 2016 Langerhans cell histiocytosis (LCH) is characterized by inflammatory lesions containing pathologic CD207+ dendritic cells with constitutively activated ERK.
Rikhia Chakraborty +15 more
semanticscholar +1 more source