BRAF V600E-Positive Multisite Langerhans Cell Histiocytosis in a Preterm Neonate [PDF]
Hemorrhagic pustules with a “blueberry muffin” appearance accompanied by respiratory failure in a neonate present a challenging differential diagnosis that includes infections and neoplasms.
Aslam, Muhammad +8 more
core +3 more sources
Rare Presentation of a Rare Orthopedic Pathology: Erdheim Chester Disease [PDF]
In 1930, William Chester and pathologist Jakob Erdheim discovered the pathology currently known as Erdheim Chester disease. There are only approximately 249 histologically confirmed patients to have been diagnosed with this disease as noted in the ...
Samona J, Owen J, Martin S
core +1 more source
Histiocytes: Multifaceted Regulators of Health and Disease
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley +1 more source
CASES OF DISSEMINATED AND GIANT JUVENILE XANTHOGRANULOMA IN CHILDREN
Juvenile xanthogranuloma is the most common clinical variant of the class II histiocytosis. This article presents two clinical observationsof papulonodular juvenile xanthogranuloma, specification of epidemiological data, clinical and histological ...
E. I. Pil'gui +5 more
doaj +1 more source
Localized Langerhans cell histiocytosis masquerading as Brodie s abscess in a 2-year-old child: a case report [PDF]
Langerhans cell histiocytosis (LCH), formerly known as histiocytosis X, refers to a spectrum of diseases characterized by idiopathic proliferation of histiocytes that produce either focal (localized LCH) or systemic manifestations (Hand–Schüller ...
Chang, Wei-Fang +4 more
core +1 more source
Treatment of Reactive Histiocytosis With Oclacitinib: A Retrospective Case Series of 10 Dogs
Background: Canine reactive histiocytosis is a proliferative disorder of activated interstitial dendritic cells with cutaneous and systemic forms. An immune‐mediated aetiology is likely, and systemic immunomodulatory agents such as corticosteroids, tetracycline/niacinamide, ciclosporin, azathioprine and leflunomide have been employed for its management.
Christine L. Cain +2 more
wiley +1 more source
Sotatercept in Pulmonary Langerhans Cell Histiocytosis‐Associated Pulmonary Hypertension: A Case Series and Systematic Review [PDF]
ABSTRACT Pulmonary Langerhans cell histiocytosis (PLCH) frequently complicated by pulmonary hypertension (PH), which markedly worsens prognosis. We retrospectively reviewed three institutional PLCH‐PH cases treated with off‐label Sotatercept added to background triple therapy and performed a systematic review of published PLCH‐PH reports (PubMed/Embase
Chilingarashvili G +7 more
europepmc +2 more sources
What's new? Childhood cancer ranks among the leading causes of disease‐related deaths in children in high‐income countries. Established risk factors, however, account for only a small proportion of incident childhood cancers. In this report, the authors present the first long‐term assessment of temporal trends in childhood cancer incidence rates in ...
Friederike Erdmann +8 more
wiley +1 more source
Histiocytosis X and Bronchopulmonary Adenocarcinoma: A Rare Coexistence
There exists a rarely observed association between pulmonary histiocytosis X and bronchopulmonary cancer. However, the frequency of bronchopulmonary cancer in these patients is higher than in the general population.
Akýn Kaya +5 more
doaj +1 more source
ALK-Positive Histiocytosis: A Case Report and Literature Review
ALK positive histiocytosis is a relatively new histiocytic proliferation disease with a characteristic gene translocation involving fusion of the ALK gene with different partners, mostly KIF5B.
Omar Issa JABER +3 more
doaj +1 more source

