Novel report of an osteogenic tumor in a late Jurassic Mamenchisaurid from Thailand
Here we describe a pathology in an ulna of a Late Jurassic mamenchisaurid from Thailand. We use anatomical descriptions, CT scanning, and bone histology to identify the pathology as an osteogenic tumor. Abstract Here we report on an osseous abnormality and multiple fractures in an ulna of a subadult basal Eusauropod (Mamenchisauridae) from the Late ...
Siripat Kaikaew+2 more
wiley +1 more source
Introduction: Langerhans cell histiocytosis (LCH) is an abnormal clonal proliferation of Langerhans cells secondary to immune process, mutation of oncogene or genetic predispositions. It preferentially affects bone, lung and skin.
Morcel Marion+5 more
doaj +1 more source
Choroidal Neovascular Membrane Formation and Retinochoroidopathy in a Patient with Systemic Langerhans Cell Histiocytosis: A Case Report and Review of the Literature [PDF]
We report a case of bilateral atrophic retinochoroidopathy with choroidal neovascular membrane (CNVM) formation in a patient with systemic Langerhans cell histiocytosis (LCH).
Foster, Charles Stephen+3 more
core +2 more sources
Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis.
Langerhans cell histiocytosis (LCH) is characterized by inflammatory lesions containing pathologic CD207+ dendritic cells with constitutively activated ERK.
Rikhia Chakraborty+15 more
semanticscholar +1 more source
BRAFV600E mutation in cutaneous lesions of patients with adult Langerhans cell histiocytosis. [PDF]
BACKGROUND: Langerhans cell histiocytosis (LCH) is characterized by the proliferation of pathologic Langerhans cells. The disease can develop in any age and can affect almost any organ. Cutaneous involvement is frequent in LCH.
Badalian-Very+18 more
core +4 more sources
Steroid‐responsive generalised sterile necrotising pyogranulomatous lymphadenitis in a cat
A 1.5‐year‐old neutered male cat was presented with fever, inappetence, lethargy and marked generalised lymphadenopathy of 4 days duration. Excisional biopsy of peripheral lymph nodes revealed necrotising pyogranulomatous lymphadenitis. Extensive investigation failed to identify an underlying infectious [bacterial (Bartonella, Mycobacteria, Mycoplasma,
L. Lecot+4 more
wiley +1 more source
Impact of BRAFV600E mutation on aggressiveness and outcomes in adult clonal histiocytosis
Histiocytoses encompass a wide spectrum of diseases, all characterized by tissue infiltration by CD68+ histiocytes. Most adult histiocytoses are considered clonal diseases because they highlight recurrent somatic mutations in the MAP-kinase pathway gene,
Jerome Razanamahery+5 more
doaj +1 more source
Indeterminate Cell Histiocytosis: A Case Report [PDF]
Indeterminate cell histiocytosis is a rare neoplasm composed of cells with mixed characteristics of Langerhans cells and non-Langerhans cells. An otherwise healthy, 36-year-old woman presented with asymptomatic generalized papules and nodules that had ...
Chen, Gwo-Shing, Wang, Chun-Hua
core +2 more sources
Demonstration of BRAF-V600E in Rosai-Dorfman-Destombes disease requires sensitive molecular assays and molecular-based tissue immunostain. BRAF-V600E blood testing is important for disease-monitoring BRAF-mutated histiocytosis and can guide inhibitor ...
R. Mastropolo+5 more
semanticscholar +1 more source
Histiocytoid Sweet Syndrome With Paradoxical Neutropenia in a Pediatric Patient
ABSTRACT Histiocytoid Sweet syndrome (HSS) is a rare inflammatory skin condition characterized by the infiltration of mononuclear cells in the dermis and leukocytosis with neutrophilia. This uncommon variant of classic Sweet syndrome is rarely reported in the literature, especially in pediatric patients.
Shelby Boock+3 more
wiley +1 more source