CD30 as a Target Molecule in the Diagnosis and Therapy of Lymphomas
ABSTRACT The tumor necrosis factor (TNF)‐receptor superfamily 8 receptor CD30 molecule is expressed in all tumor cells of Hodgkin lymphoma and anaplastic large cell lymphoma but is only weakly expressed in a small subset of large lymphoid cells in normal peripheral lymphoid tissues.
Harald Stein, Brunangelo Falini
wiley +1 more source
Cutaneous horn: A rare subtype of juvenile xanthogranuloma
Because of variability in the JXG shape and the extensive range of a cutaneous horn differential diagnosis, dermatologists should keep this diagnosis in their mind in the time of encountering with infants or children cases of cutaneous horn.
Fariba Iraji +2 more
doaj +1 more source
Single-agent dabrafenib for BRAFV600E-mutated histiocytosis
Langerhans cell histiocytosis (LCH) and Erdheim-Chester disease (ECD) are clonal disorders of the monocyte/macrophage and dendritic cell lineages characterized by infiltration of histiocytes, acute and chronic inflammation, and fibrosis that can involve ...
A. Bhatia +11 more
semanticscholar +1 more source
New cases expand the genotype, phenotype and therapeutic landscape of H syndrome
British Journal of Haematology, EarlyView.
Clément Triaille +10 more
wiley +1 more source
What's New? Investigating the spectrum of (likely) pathogenic germline variants (LP/PVs) in hereditary breast and ovarian cancer (HBOC) genes in pediatric malignancies by unselected genotyping identified 44% (12/27) of clinically unsuspected cases. Burden testing demonstrated considerable associations between monoallelic LP/PVs in five HBOC genes and ...
Katharina Daugs +11 more
wiley +1 more source
Langerhans cell histiocytosis: current concepts in dentistry and case report [PDF]
Langerhans cell histiocytosis (LCH), which is a rare granulomatous pediatric disease of unknown etiology, is characterized by the idiopathic proliferation and accumulation of abnormal and clonal Langerhans cells or their ...
Alejo-Gonzalez, Francisco +4 more
core
Tissue‐Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts
ABSTRACT Although all myeloid cells are considered to derive from hematopoietic stem cells, the cells in each myeloid lineage are heterogeneous populations, and their distribution and functions vary, depending on underlying physiologic and pathologic processes, age, sex, and genetic and epigenetic signatures.
Peter Valent +27 more
wiley +1 more source
BRAF V600E-Positive Multisite Langerhans Cell Histiocytosis in a Preterm Neonate [PDF]
Hemorrhagic pustules with a “blueberry muffin” appearance accompanied by respiratory failure in a neonate present a challenging differential diagnosis that includes infections and neoplasms.
Aslam, Muhammad +8 more
core +3 more sources
Recurrent Pneumothorax Revealing Lymphangioleiomyomatosis in a Young Woman: A Case Report
ABSTRACT Lymphangioleiomyomatosis (LAM) should be considered in young women presenting with recurrent pneumothorax. Early diagnosis through high‐resolution computed tomography(HRCT)and histopathological analysis is essential for timely management and improved patient outcomes.
Qihang Zhang +3 more
wiley +1 more source
Multisystem Langerhans' cell histiocytosis (Hand-Schüller-Christian disease) in an adult: a case report and review of the literature [PDF]
Langerhans' cell histiocytosis (LCH) is a rare and enigmatic clonal disorder that affects mainly children. It is characterized by single or multiple granulomatous mass lesions composed of cells with the Langerhans' cell phenotype.
Jaques, B. +3 more
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