Results 101 to 110 of about 71,897 (258)

Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]

, 2015
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam, Kerber, Sarah, Pluschke, Gerd, Zimmer, Gert   +3 more
core   +3 more sources

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Recipients with blood group A associated with longer survival rates in cardiac valvular bioprostheses

EBioMedicine, 2019
Background: Pigs/bovines share with humans some of the antigens present on cardiac valves. Two such antigens are: the major xenogenic Ag, “Gal” present in all pig/bovine very close to human B-antigen of ABO-blood-group system; the minor Ag, pig histo ...
O. Schussler, N. Lila, T. Perneger, P. Mootoosamy, J. Grau, A. Francois, D.M. Smadja, Y. Lecarpentier, M. Ruel, A. Carpentier   +9 more
doaj   +1 more source

A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface. [PDF]

PLoS Pathogens, 2015
Norovirus (NoV) causes epidemic acute gastroenteritis in humans, whereby histo-blood group antigens (HBGAs) play an important role in host susceptibility.
Wu Liu, Yutao Chen, Xi Jiang, Ming Xia, Yang Yang, Ming Tan, Xuemei Li, Zihe Rao   +7 more
doaj   +1 more source

Polyfunctional Melan-A-specific tumor-reactive CD8+ T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS [PDF]

, 2016
The identification of activation pathways linked to anti-tumor T-cell polyfunctionality in long surviving patients is of great relevance in the new era of immunotherapy.
Belinda, Palermobc, Cosmo Di, Donnac, GISMONDI, Angela, Isabella, Sperdutid, Ornella, Franzesea, SANTONI, Angela, STABILE, MARIA HELENA, Virginia, Ferraresie   +7 more
core   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Development of a Surrogate Neutralization Assay for Norovirus Vaccine Evaluation at the Cellular Level

Viruses, 2018
Noroviruses (NoVs) are the main pathogens responsible for sporadic and epidemic nonbacterial gastroenteritis, causing an estimated 219,000 deaths annually worldwide.
Xiaoli Wang, Shuxia Wang, Chao Zhang, Yu Zhou, Pei Xiong, Qingwei Liu, Zhong Huang   +6 more
doaj   +1 more source

The Association between Symptomatic Rotavirus Infection and Histo-Blood Group Antigens in Young Children with Diarrhea in Pretoria, South Africa

Viruses, 2022
Objectives: Recently, histo-blood group antigens (HBGAs) have been identified as receptors or attachment factors of several viral pathogens. Among rotaviruses, HBGAs interact with the outer viral protein, VP4, which has been identified as a potential ...
Kebareng Rakau, Maemu Gededzha, Ina Peenze, Pengwei Huang, Ming Tan, Andrew Duncan Steele, Luyanda Mapaseka Seheri   +6 more
doaj   +1 more source

Norovirus Infection and Disease in an Ecuadorian Birth Cohort: Association of Certain Norovirus Genotypes With Host FUT2 Secretor Status. [PDF]

, 2015
BACKGROUND: Although norovirus is the most common cause of gastroenteritis, there are few data on the community incidence of infection/disease or the patterns of acquired immunity or innate resistance to norovirus.
Broncano, N, Chico, ME, Collins, N, Cooper, PJ, Costantini, V, Gregoricus, N, Lopman, BA, Parashar, U, Sandoval, C, Trivedi, T, Vaca, M, Vicuña, Y, Vinjé, J   +12 more
core   +1 more source

Histo-Blood Group Antigen Presentation Is Critical for Binding of Norovirus VLP to Glycosphingolipids in Model Membranes.

ACS Chemical Biology, 2017
Virus entry depends on biomolecular recognition at the surface of cell membranes. In the case of glycolipid receptors, these events are expected to be influenced by how the glycan epitope close to the membrane is presented to the virus. This presentation
Waqas Nasir, M. Frank, A. Kunze, M. Bally, F. Parra, P. Nyholm, F. Höök, G. Larson   +7 more
semanticscholar   +1 more source