Results 141 to 150 of about 71,897 (258)

Alternative Polyadenylation Contributes to Fibroblast Senescence in Pulmonary Fibrosis

Aging Cell, Volume 24, Issue 10, October 2025.
In aging or fibrotic fibroblasts, NUDT21 is downregulated, leading to alternative polyadenylation/3′ UTR shortening of STAT3 pathway genes, enhancing their protein expression and promoting STAT3 phosphorylation. Activated STAT3 signaling subsequently drives the expression and release of senescence‐associated secretory phenotype (SASP) factors, thereby ...
Jingjing Huang, Maria Jose Gacha‐Garay, Yu Wang, Scott D. Collum, Rene A. Girard, Hydia Puente, Seung‐Hee Yoo, Rahat Hussain, Jayeshkumar Patel, Manish Patel, Eric J. Wagner, Hari KrishnaYalamanchili, Harry Karmouty‐Quintana, Zheng Chen, Tingting Mills   +14 more
wiley   +1 more source

B cell lines fail to support efficient rhesus enteric calicivirus and human norovirus replication

Journal of Virology
Analyses of intestinal biopsies of infected individuals and/or nonhuman primates (NHP) suggested the possible immune cell tropism of human noroviruses (HuNoV) and rhesus enteric caliciviruses (ReCV).
Tibor Farkas
doaj   +1 more source

Mucosal Mast Cells Response in the Jejunum of Ascaridia Galli-Infected Laying Hens [PDF]

, 2013
Intestinal defense mechanism against helminthes parasitic nematode to be associated with mucosal mast cells reaction. The aim of this research was to examine the effect of infection by Ascaridia galli parasite to trigger mucosal defense based on mucosal ...
Balqis, U. (U), Darmawi, D. (Darmawi), Frengki, F. (Frengki), Hambal, M. (M), Priosoeryanto, B. P. (B)   +4 more
core  

Histo-blood group antigens of glycosphingolipids predict susceptibility of human intestinal enteroids to norovirus infection [PDF]

, 2020
Inga Rimkutė, Konrad Thorsteinsson, Marcus Henricsson, Victoria R. Tenge, Xiaoming Yu, Shih‐Ching Lin, Kei Haga, Robert L. Atmar, Nils Lycke, Jonas Nilsson, Mary K. Estes, Marta Bally, Göran Larson   +12 more
openalex   +1 more source

Detection of Gliadin‐Activated CD4+ T Cells Is a New Assay to Reveal Pathogenic Lymphocytes in Celiac Disease

Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.
ABSTRACT The diagnosis of celiac disease (CD) relies on the presence of serum antibodies against type 2‐tissue transglutaminase (tTG2) and endomysium, which in adult patients must be confirmed by assessing small intestinal mucosa damage through esophagogastroduodenoscopy.
Laura Pisapia, Marcella D'Ambrosio, Ilaria Mottola, Stefania Picascia, Domenico De Girolamo, Fabiana Castiglione, Nadia Tinto, Antonio Rispo, Carmen Gianfrani, Giovanna Del Pozzo   +9 more
wiley   +1 more source

Expression of inflammation-related genes is associated with adipose tissue location in horses [PDF]

, 2013
Background : In humans, adipose tissue (AT) originating from different depots shows varying gene expression profiles. In horses, the risk of certain metabolic disorders may also be influenced by the impact of specific AT depots.
Bruynsteen, Lien, Ducatelle, Richard, Erkens, Tim, Harris, Patricia, Hesta, Myriam, Janssens, Geert, Peelman, Luc   +6 more
core   +2 more sources

Evidence for human norovirus infection of dogs in the United kingdom. [PDF]

, 2015
Human noroviruses (HuNoVs) are a major cause of viral gastroenteritis, with an estimated 3 million cases per year in the United Kingdom. HuNoVs have recently been isolated from pet dogs in Europe (M. Summa, C.-H. von Bonsdorff, and L.
Belliot, Gael, Brownlie, Joe, Caddy, Sarah L, de Rougemont, Alexis, El-Attar, Laila, Emmott, Edward, Goodfellow, Ian, Hollinshead, Michael, Le Pendu, Jacques, Mitchell, Judy A   +9 more
core   +5 more sources

Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis [PDF]

, 2013
PMCID: PMC3856490This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Amor, S, Baker, D, Beyer, C, Gerritsen, W, Huizinga, R, Kipp, M, Peferoen-Baert, R, Pryce, G, Puentes, F, Reijerkerk, A, Ummenthum, K, van der Star, BJ, van der Valk, P, Victor, M   +13 more
core   +5 more sources

Pathogenesis of polymyalgia rheumatica [PDF]

, 2018
Polymyalgia rheumatica (PMR) is a chronic, inflammatory disorder of unknown cause, almost exclusively occurring in people aged over 50 and often associated with giant cell arteritis.
Ciccia F., Ferrante A., Guggino G., Macaluso F., Triolo G.   +4 more
core   +1 more source

Histo-blood group antigen profile of Australian Aboriginal children and seropositivity following oral rotavirus vaccination.

Vaccine, 2023
B. Middleton, M. Danchin, N. Cunliffe, Mark A. Jones, Karen Boniface, Carl D. Kirkwood, S. Gallagher, Lea-Ann Kirkham, C. Granland, Monica M. McNeal, C. Donato, N. Bogdanovic-Sakran, Amanda Handley, J. Bines, Thomas Snelling   +14 more
semanticscholar   +1 more source