Results 201 to 210 of about 249,831 (220)
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Histo‐Blood Group Antigens as Allo‐ and Autoantigens
Annals of the New York Academy of Sciences, 2005Abstract: The science of blood groups has made giant steps forward during the last decade. Blood‐group typing of red blood cells (RBCs) is performed on more than 15 million samples per year in Europe, today much less often for forensic reasons than for clinical purposes such as transfusion and organ transplantation.
Hendrik Tevaearai +6 more
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ABH and Lewis histo‐blood group antigens in cancer
APMIS, 2001Antigens of the ABH and Lewis histo‐blood group family can be found on many normal cells, mainly of epithelial type. In carcinomas, altered expression of the various carbohydrate epitopes of this family occur, and are often strongly associated with either a good or bad prognosis.
Béatrice Le Moullac-Vaidye +5 more
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Expression of histo-blood group antigens in vertebrate gonads
Acta Biologica Hungarica, 2010The tissue expression of human histo-blood group antigens (HBGA) in vertebrates, as well as their evolutionary tendencies and relation to histogenesis, especially in the reproductive system, are not entirely understood.The present research comprises a large-scale immunohistochemical study of HBGA A and B expression in ovaries and testicles of 14 ...
Tomova, Elena, Sarafian, Victoria
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Histo‐blood group antigens in human fetal thymus and in thymomas
APMIS, 1996The glycosylation of epithelial cell surface antigens follows cellular differentiation, and changes in the pattern of expression are seen in various premalignant and malignant epithelial lesions. The distribution of type‐2 chain ABH‐carbohydrate structures (N‐acetyl‐lactosamine, H‐type 2 chain, Le‐y, Le‐x and sialyl‐Le‐x) of the ABO‐histo‐blood group ...
Engel, P +3 more
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ABH Histo-Blood Group Antigens in Human Thymus Involution
Archives of Medical Research, 2006Human histo-blood group antigens (HBGA) are genetically determined glycoproteins supposed to participate in cell differentiation, adhesion, cancer metastasis and angiogenesis. In tissues, HBGA are mostly expressed in epithelial cells (EC). The EC comprising the thymocyte microenvironment play an important role in the ontogeny of the thymus.
Tsvetana T. Marinova, Victoria Sarafian
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Synthesis of ABO histo-blood group type I and II antigens
Carbohydrate Research, 2009The ABO histo-blood group antigens have long been of interest to chemists, biochemists, and evolutionary biologists. However, to date, a complete synthesis of all ABO histo-blood group antigens has not been conducted, despite the potential for such a panel to provide a more detailed understanding of the biological roles of these glycan motifs.
Todd L. Lowary, Peter J. Meloncelli
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Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies
Journal of Virology, 2023Human noroviruses are highly contagious and a major problem in closed institutions, such as schools, hospitals, and cruise ships. Reducing norovirus infections is challenging on multiple levels and includes the frequent emergence of antigenic variants, which complicates designing effective, broadly reactive capsid therapeutics.
Gargi Kher +8 more
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Histo-blood group antigens: a common niche for norovirus and rotavirus
Expert Reviews in Molecular Medicine, 2014Noroviruses (NoVs) and rotaviruses (RVs), the two most important causes of viral acute gastroenteritis, are found to recognise histo-blood group antigens (HBGAs) as receptors or ligands for attachment. Human HBGAs are highly polymorphic containing ABO, secretor and Lewis antigens.
Ming Tan, Xi Jiang
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LAMPs and ABH histo‐blood group antigens in granulation tissue
APMIS, 2007Endothelial cells are major participants in angiogenic processes accompanying wound repair. The functions of ABH histo‐blood group antigens (HBGAs) and lysosome‐associated membrane proteins LAMP‐1 and LAMP‐2 in endothelial cells of granulation tissue are currently unkown. Here we hypothesize that HBGAs and LAMPs enrich the phenotypic characteristics of
Victoria Sarafian, Dorian Dikov
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Binding activity of norovirus and sapovirus to histo-blood group antigens
Archives of Virology, 2006Noroviruses (NoVs) and sapoviruses (SaVs) are causative agents of human gastroenteritis. There is increasing evidence that certain human NoV strains bind to histo-blood group antigens (HBGAs). We found that several NoV virus-like particles (VLPs) showed binding activity to HBGAs, while neither SaV genogroup I (GI) VLP nor SaV GV VLP showed such ...
Grant S. Hansman +4 more
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