Results 161 to 170 of about 115,135 (343)

What is the role of alternate splicing in antigen presentation by major histocompatibility complex class I molecules?

open access: green, 2009
Alan Belicha‐Villanueva   +5 more
openalex   +2 more sources

Optimization of CEST MRI Reporter Protein Design Using Cation‐Pi Networks

open access: yesChemistry – A European Journal, EarlyView.
A novel engineering approach can produce reporter proteins for cell and viral therapy tracking with unique magnetic resonance imaging (MRI) signatures, detectable with chemical exchange saturation transfer (CEST). We discover how cation‐π interactions between amino acid groups can help us fine‐tune magnetic resonance properties for noninvasive ...
David E. Korenchan   +8 more
wiley   +1 more source

Organization of the AKR Qa region [PDF]

open access: yes, 1989
Bevec, Dorian   +6 more
core   +1 more source

Foundational Principles for the Quantitative Translation of T‐Cell Therapeutics for Hematologic Malignancies and Immunology

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
T‐cell engaging antibodies (TCEs) and chimeric antigen receptor (CAR) T cells (CAR‐T cells) are among precision medicine therapies that have revolutionized the treatment of hematologic cancers. Their success in oncology has piqued interest in translating this promise into additional indications, such as autoimmune disorders.
Peter Ashcroft   +6 more
wiley   +1 more source

Infiltrating CD45RC− T cells are associated with immunologic unresponsiveness induced by donor class I major histocompatibility complex antigens in rats [PDF]

open access: bronze, 1998
Yasuo Yamaguchi   +10 more
openalex   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

open access: yesBarrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Transcriptomic and proteomic profiling shows dysregulated immune and metabolic pathways in arrhythmogenic cardiomyopathy

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Arrhythmogenic cardiomyopathy (ACM) is a hereditary heart disease characterized by fibrofatty myocardial replacement and a predisposition to malignant ventricular arrhythmias. The underlying pathomechanisms remain incompletely understood, and specific disease markers are sparse.
Deniz Akdis   +11 more
wiley   +1 more source

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