Results 181 to 190 of about 115,135 (343)

Posttranslationally modified self-peptides promote hypertension in mouse models

The Journal of Clinical Investigation
Posttranslational modifications can enhance immunogenicity of self-proteins. In several conditions, including hypertension, systemic lupus erythematosus, and heart failure, isolevuglandins (IsoLGs) are formed by lipid peroxidation and covalently bond ...
Nathaniel Bloodworth, Wei Chen, Kuniko Hunter, David Patrick, Amy Palubinsky, Elizabeth Phillips, Daniel Roeth, Markus Kalkum, Simon Mallal, Sean Davies, Mingfang Ao, Rocco Moretti, Jens Meiler, David G. Harrison   +13 more
doaj   +1 more source

Molecular Mechanism for the Selective Presentation of Antigenic Peptides by Major Histocompatibility Complex Class I and Class II Molecules: A Hypothesis. [PDF]

Curr Issues Mol Biol
Zhu BT.
europepmc   +1 more source

Induction of class I major histocompatibility complex antigen expression by West Nile virus on gamma interferon-refractory early murine trophoblast cells.

, 1989
Nicholas J. C. King, L.E. Maxwell, Alison Kesson   +2 more
openalex   +2 more sources

Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation [PDF]

, 2017
Marek Wieczorek, Esam T. Abualrous, Jana Sticht, Miguel Álvaro‐Benito, Sebastian Stolzenberg, Frank Noé, Christian Freund   +6 more
openalex   +1 more source

Multi‐omics profiling identified two epithelioid sarcoma molecular subtypes with distinct signaling and immune characteristics

Cancer Communications, EarlyView.
Carine Ngo, Léo Colmet‐Daage, Julien Vibert, Clémence Hénon, Daniel Pissaloux, Alexander Valent, Jia Xiang Jin, Riwan Brillet, Julien Masliah‐Planchon, Gaëlle Pierron, Ludovic Lacroix, Etienne Rouleau, Cyril Roussel‐Simonin, Lilian Lecorgne, Clémence Astier, Marlène Garrido, Rastislav Bahleda, Benjamin Verret, Axel Le Cesne, Charles Honore, Matthieu Faron, Wolf Herman Fridman, Catherine Sautès‐Fridman, Jean‐Michel Coindre, Jean‐Yves Scoazec, Joshua J Waterfall, Franck Bourdeaut, Thomas G. P. Grünewald, Jean‐Yves Blay, Franck Tirode, Sophie Postel‐Vinay   +30 more
wiley   +1 more source

Processing and Major Histocompatibility Complex Class II Presentation ofLegionella pneumophilaAntigens by Infected Macrophages

, 2005
Annie L. Neild, Takahiro Murata, Craig R. Roy   +2 more
openalex   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

Immunocompatibility in transplantation: adapting to a changing therapeutic landscape. [PDF]

Front Immunol
Güell-Alonso R, Cabrera-Pérez R, Vives J.   +2 more
europepmc   +1 more source

Parkinson's‐Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa

Movement Disorders, EarlyView.
Abstract Background Peripheral disease mechanisms such as immune dysregulation may contribute to Parkinson's disease (PD). To investigate interactions between common PD mutations and immune responses to environmental pathogens, we studied responses to Pseudomonas aeruginosa (P.
Julian R. Mark, Hannah A. Staley, Ann M. Titus, Julian Agin‐Liebes, Alicia Garrido, Laura Hughes, Nicolas Dzamko, Rebecca L. Wallings, Malú Gámez Tansey   +8 more
wiley   +1 more source

Biological mechanism and immune response of MHC-II expression in tumor cells. [PDF]

Cancer Biol Med
Zhou M, Pan S, Zhang Y, Hu C, Xu Z.
europepmc   +1 more source