Results 221 to 230 of about 115,135 (343)

Delivery of Exogenous Protein Antigens to Major Histocompatibility Complex Class I Pathway in Cytosol [PDF]

, 2002
Huyen Cao, Deepak Agrawal, Nicholas Kushner, Neal Touzjian, Max Essex, Yichen Lu   +5 more
openalex   +1 more source

Major histocompatibility class I antigenic peptides derived from translation of pre-mRNAs generate immune tolerance

, 2023
Ewa Sroka, Mathilde Lavigne, Marika Pla, Chrysoula Daskalogianni, Maria Camila Tovar-Fernandez, Rodrigo Prado Martins, Bénédicte Manoury, Guillaume Darrasse-Jèze, Megane Nascimento, Sébastien Apcher, Robin Fåhræus   +10 more
openalex   +2 more sources

Biomolecular Interaction Prediction in the Pre‐ and Post‐AlphaFold Era: The 8th CAPRI Evaluation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We report on the 8th CAPRI Evaluation period, capturing the assessment of CAPRI Rounds 47 to 55 (excluding the CASP and COVID‐related Rounds), which have witnessed the transition to AI‐driven prediction tools such as AlphaFold and related alternatives. The prediction Rounds in this evaluation are characterized by a high level of difficulty due
Marc F. Lensink, Nessim Raouraoua, Guillaume Brysbaert, Sameer Velankar, Shoshana J. Wodak, Alexandre M. J. J. Bonvin   +5 more
wiley   +1 more source

Structural changes from wild-type define tumor-rejecting neoantigens. [PDF]

J Immunother Cancer
Adams AC, Macy AM, Borden ES, Herrmann LM, Brambley CA, Sonar SA, Ma T, Li X, Hughes A, Roe DJ, Mangold AR, Nikolich JZ, Buetow KH, Wilson MA, Baker BM, Hastings KT.   +15 more
europepmc   +1 more source

Structural and Functional Identification of Major Histocompatibility Complex Class I-restricted Self-peptides as Naturally Occurring Molecular Mimics of Viral Antigens [PDF]

, 2001
Denis Hudrisier, Joëlle Riond, Odile Burlet‐Schiltz, Matthias G. von Herrath, Hanna Lewicki, Bernard Monsarrat, Michael B. A. Oldstone, Jean Edouard Gairin   +7 more
openalex   +1 more source

A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.
ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada, Mary P. Choules, Frances A. Brightman, Shigeru Takeshita, Shinsuke Nakao, Nobuaki Amino, Takeshi Nakayama, Masato Takeuchi, Kanji Komatsu, Fernando Ortega, Hitesh Mistry, David Orrell, Christophe Chassagnole, Peter L. Bonate   +13 more
wiley   +1 more source

The use of MHC class I or class II 'knock out' mice to investigate the role of these antigens in allosensitization [PDF]

, 1995
Demetris, AJ, Fu, F, Fung, JJ, Gao, L, Li, Y, Lu, L, Noyola, H, Qian, S, Rao, AS, Starzl, TE, Thomson, AW   +10 more
core  

Identification of murine H-2Db histocompatibility antigens in cells transfected with cloned H-2 genes [PDF]

, 1985
Ferluga, J., Festenstein, H., Schmidt, Walter, Weiss, Elisabeth H.   +3 more
core   +1 more source

Soluble class I histocompatibility antigens (s-HLA) and β2-microglobulin at delivery [PDF]

, 1991

openalex   +1 more source

Mathematical Modeling of Neuroinflammation in Neurodegenerative Diseases

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Age‐related neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD) and Parkinson's disease (PD) are an increasing public health concern. Whereas the pathology of these diseases is complex, chronic central inflammation, or neuroinflammation, is commonly observed across many neurodegenerative diseases ...
Alex Foster‐Powell, Amin Rostami‐Hodjegan, Guy Meno‐Tetang, Donald E. Mager, Kayode Ogungbenro   +4 more
wiley   +1 more source