Results 311 to 320 of about 453,877 (390)

The impact of BTK knockdown on lung adenocarcinoma growth and immune response

Cancer Science, EarlyView.
First study on BTK's role in LUAD progression. Low BTK expression associated with poor LUAD prognosis. Abstract This study explores the molecular role of the BTK gene in lung adenocarcinoma (LUAD) progression and patient prognosis. Using a radiomics model based on BTK expression and PET‐CT data analyzed through DeeplabV3, alongside transcriptomic and ...
Jilan Huang, Yufan Yuan, Linghong Guo, Guojin Xia, Yan Chen, Qi Chen, Min Wang   +6 more
wiley   +1 more source

In Silico Targeting and Immunological Profiling of PpiA in <i>Mycobacterium tuberculosis</i>: A Computational Approach. [PDF]

Pathogens
Nasiri MJ, Rogowski L, Venketaraman V.
europepmc   +1 more source

Disruption of Hydrogen Bonds between Major Histocompatibility Complex Class II and the Peptide N-Terminus Is Not Sufficient to Form a Human Leukocyte Antigen-DM Receptive State of Major Histocompatibility Complex Class II

, 2013
Monika‐Sarah E. D. Schulze, Anne-Kathrin Anders, Dhruv K. Sethi, Melissa Call   +3 more
openalex   +2 more sources

High Antigenicity for Treg Cells Confers Resistance to PD‐1 Blockade Therapy via High PD‐1 Expression in Treg Cells

Cancer Science, Volume 116, Issue 5, Page 1214-1226, May 2025.
High antigenicity of Treg cells confers resistance to anti‐PD‐1 mAb monotherapy via high PD‐1 expression in Treg cells. Resistance to anti‐PD‐1 mAb monotherapy via high PD‐1 expression in Treg cells can be overcome by combination therapy with an anti‐CTLA‐4 mAb.
Hiroaki Matsuura, Takamasa Ishino, Toshifumi Ninomiya, Kiichiro Ninomiya, Kota Tachibana, Akiko Honobe‐Tabuchi, Yoshinori Muto, Takashi Inozume, Youki Ueda, Kadoaki Ohashi, Yoshinobu Maeda, Joji Nagasaki, Yosuke Togashi   +12 more
wiley   +1 more source

Evaluation of the Frequency of HLA-DQ2/DQ8 Genes Among Patients with Celiac Disease and Those on a Gluten-Free Diet. [PDF]

Foods
Kowalski MK, Domżał-Magrowska D, Małecka-Wojciesko E.   +2 more
europepmc   +1 more source

Delayed onset of graft-versus-host disease in immunodeficent human leucocyte antigen-DQ8 transgenic, murine major histocompatibility complex class II-deficient mice repopulated by human peripheral blood mononuclear cells

, 2013
Sarah M. Büchner, Katja Sliva, Halvard Bönig, Iris Völker, Zoe Waibler, Jörg Kirberg, Barbara S. Schnierle   +6 more
openalex   +2 more sources

Differentiation of Cytotoxic CD8+ T Cell Subsets Under Tumor Progression: Can CD69 Be a New Therapeutic Target?

Cancer Science, EarlyView.
This review summarizes the current understanding of cytotoxic CD8+ T cell subset differentiation under tumor progression and highlights the crucial role of chronic CD8+ T cell responses in anti‐tumor immunity. CD69 is an important regulator of chronic CD8+ T cell response that contributes to the induction of the Tox gene via calcineurin/NFAT signaling.
Ryo Koyama‐Nasu, Yangsong Wang, Hinata Miyano, Motoko Y. Kimura   +3 more
wiley   +1 more source

Development of a multi-epitope chimeric vaccine in silico against Babesia bovis, Theileria annulata, and Anaplasma marginale using computational biology tools and reverse vaccinology approach. [PDF]

PLoS One
Siddiki AZ, Alam S, Fuad Bin Hossen F, Alim MA.   +3 more
europepmc   +1 more source

In Vitro Expansion and Transduction of Primary NK Cells Using Feeder Cells Expressing Costimulatory Molecules and IL‐21

Cancer Science, EarlyView.
Our findings show that feeder cells expressing CD80, 41BBL and membrane‐bound IL‐21 promote optimal NK cell expansion. We also evaluated CAR transduction efficiency into expanded NK cells using different lentiviral vectors. The results indicate that NK cells transduced with the BaeV lentivirus exhibit high cytotoxicity toward target cells.
Thi Bao Tram Tran, Thi Van Anh Bui, Thi Minh Thu Tran, Nguyen Minh Nguyen, Hoang Thien Phuc Nguyen, Thi Phuong Diem Tran, Duc Minh Quan Nguyen, Thai Minh Quan Ngo, Thanh Binh Nguyen, Els Verhoeyen, Nhat Thang Tran, Hoai‐Nghia Nguyen, Le Son Tran   +12 more
wiley   +1 more source

PIPLOM: prediction of exogenous peptide loading on major histocompatibility complex class I molecules. [PDF]

Bioinform Adv
Schmidt F, Wu K, Gerber L, Chioh Wen Jing F, Pedrosa D, Wong Choon Lim G, Wirawan M, Eng C, Fink K, MacLeod DT, Fehlings M, Wilm A.   +11 more
europepmc   +1 more source