Results 331 to 340 of about 453,877 (390)

The Landmark Series: Cancer Vaccines for Solid Tumors. [PDF]

Ann Surg Oncol
Ninmer EK, Xu F, Slingluff CL.
europepmc   +1 more source

Type 1 Diabetes: A Guide to Autoimmune Mechanisms for Clinicians

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Type 1 diabetes (T1D) results from the destruction of pancreatic beta cells by autoreactive T lymphocytes, leading to insulin deficiency and lifelong insulin dependence. It develops in genetically predisposed individuals, triggered by environmental or immunological factors.
François‐Xavier Mauvais, Peter M. van Endert   +1 more
wiley   +1 more source

Neutrophils in Type 1 Diabetes: Untangling the Intricate Web of Pathways and Hypothesis. [PDF]

Biomolecules
Nigi L, Pedace E, Dotta F, Sebastiani G.
europepmc   +1 more source

Mesenchymal stem cell‐mediated mitochondrial transfer regulates the fate of B lymphocytes

European Journal of Clinical Investigation, EarlyView.
Mesenchymal stem cells (MSCs) modulate immune responses by transferring mitochondria to immune cells, including B lymphocytes. This study demonstrates that mitochondrial transfer to CD19+ cells is linked to reactive oxygen species levels, mitophagy and activation. Mitochondria acquisition enhances B cell viability and proliferation while downregulating
Veronika Somova, Natalie Jaborova, Bianka Porubska, Daniel Vasek, Natalie Fikarova, Martin Prevorovsky, Zuzana Nahacka, Jiri Neuzil, Magdalena Krulova   +8 more
wiley   +1 more source

Cost-Effective and Highly Scalable Typing of HLA Classes I and II Genes of up to 96 Individuals Using Nanopore Sequencing. [PDF]

HLA
Pedersen FB, Hauge AW, Hansen JF, Andersen LS, Blomsterberg S, Bruunsgaard H.   +5 more
europepmc   +1 more source

Blocking the innate immune CD1d/NKT cell axis prevents the development of cortical hyperexcitability and posttraumatic epilepsy

Epilepsia, EarlyView.
Abstract Objective Posttraumatic epilepsy (PTE) that develops after a traumatic brain injury (TBI) cannot be prevented by current treatments. Although neuroinflammation is involved in epileptogenesis, a potential role for cellular immunity in this process is largely unknown.
Xingjie Ping, Wenhui Xiong, Raj Priya, Jianyun Liu, Season K. Wyatt‐Johnson, Randy R. Brutkiewicz, Xiaoming Jin   +6 more
wiley   +1 more source

Improving long-term kidney allograft survival by rethinking HLA compatibility: from molecular matching to non-HLA genes. [PDF]

Front Genet
Mattoo A, Jaffe IS, Keating B, Montgomery RA, Mangiola M.   +4 more
europepmc   +1 more source

A walk through the development of human leukocyte antigen typing: from serologic techniques to next-generation sequencing. [PDF]

Clin Transplant Res
Choi H, Choi EJ, Kim HJ, Baek IC, Won A, Park SJ, Kim TG, Chung YJ.   +7 more
europepmc   +1 more source

Genome-wide diversity and MHC characterisation in a critically endangered freshwater turtle susceptible to disease. [PDF]

Immunogenetics
Nelson HV, Silver L, Kovacs TGL, McLennan EA, Georges A, DeGabriel JL, Hogg CJ, Belov K.   +7 more
europepmc   +1 more source

Exploring diverse approaches for predicting interferon-gamma release: utilizing MHC class II and peptide sequences. [PDF]

Brief Bioinform
Omran A, Amberg A, Ecker GF.
europepmc   +1 more source