Results 161 to 170 of about 976,058 (304)

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

Multi-resolution tone mapping for high dynamic range medical ultrasound images. [PDF]

open access: yesPLoS One
Vu TLN   +4 more
europepmc   +1 more source

Laser‐Based Sculpturing of Embedded Ultrathin Metal‐Oxide Nanopores for Enhanced Biomolecular Sensing

open access: yesAdvanced Functional Materials, EarlyView.
Controlled laser‐drilling of embedded HfO2 membranes creates three layer nanopores with Gaussian‐shaped cavities sculptured in the supporting layers. These embedded solid‐state nanopores slow DNA translocation by 12‐fold compared to SiNx pores, enabling high‐resolution, label‐free detection of short DNAs, RNAs, and proteins.
Jostine Joby   +4 more
wiley   +1 more source

Potential Role of T2-Weighted Kurtosis in Improving Response Prediction of Locally Advanced Rectal Cancer as Additional Tool Gained from Standard MRI Examination. [PDF]

open access: yesBiomedicines
Jankovic A   +14 more
europepmc   +1 more source

Roll‐to‐Roll Mechanical Exfoliation for Large‐Area van der Waals Films with Preserved Crystallographic Alignment

open access: yesAdvanced Functional Materials, EarlyView.
A roll‐to‐roll exfoliation method is demonstrated that preserves the crystallographic alignment of anisotropic 2D materials over large areas, enabling scalable fabrication of directional electronic and optoelectronic devices. Abstract Anisotropic 2D materials such as black phosphorus (BP), GeS or CrSBr, exhibit direction‐dependent optical and ...
Esteban Zamora‐Amo   +14 more
wiley   +1 more source

Prefoldin 5 is a microtubule-associated protein that suppresses Tau aggregation and neurotoxicity. [PDF]

open access: yesElife
Bisht A   +7 more
europepmc   +1 more source

Effective Sliding Motions of Vibration‐Induced Emission Stoppers in Mechanically Interlocked Molecules as Artificial Muscle Tougheners and In Situ Molecular Shuttling Sensors for Self‐Healable Mechano‐Fluorescent Polyurethane Organogels

open access: yesAdvanced Functional Materials, EarlyView.
The self‐healable ratiometric mechano‐fluorescent polyurethane (PU) organogel is constructed by incorporating a minor amount (ca. 1.5 wt.%) of the unconventional daisy chain rotaxane (as an artificial molecular muscle toughener) with specific sliding motions and ratiometric emission behaviors into the PU skeleton, which reveals the progressed intrinsic
Tu Thi Kim Cuc   +7 more
wiley   +1 more source

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