Results 101 to 110 of about 823,186 (305)

Densitometry, radiography, and histological assessment of collagen as methods to evaluate femoral bones in an experimental model of osteoporosis [PDF]

, 2011
All methods to detect experimental loss of bone present technique limitations. The sensitivities of image and histological analyses to detect the effects of teriparatide in rats with bone loss after ovariectomy were evaluated.
Ramos, A. L., A. L. Ramos, Santi, A. P., A. P. Santi, K. R. Micheletti, Cuoghi, O. A. [UNESP], L. Hernandes, O. A. Cuoghi, Hernandes, L., M. Salazar, Cuoghi, O. A., Salazar, M., Micheletti, K. R.   +12 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Quality assessments of untreated and washed quinoa (Chenopodium quinoa) seeds based on histlogical and foaming capacity investigations [PDF]

, 2010
Quinoa seed has a high nutritional value, but has a coating of bitter-tasting saponins, making it unpalatable. Therefore the seeds are usually processed in order to remove the naturally occurring saponins from the seeds.
Houben, R., Pinckaers, V.G.Z., Ossenkoppele, J.S., Lotgering, M., Raamsdonk, L.W.D., van, Groot, M.J.   +5 more
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Investigation of the protective effect of erdosteine against cyclosporine-induced injury in rat liver with histological and biochemical methods [PDF]

, 2015
Background/aim: In the present study, the protective effect of erdosteine against cyclosporine-induced injury in rat liver was investigated with histological and biochemical methods. Materials and methods: Thirty-two Wistar albino male rats were randomly
Okuyan, H.M., Karaboğa, İhsan, Motor, Sedat, Ihsan Karaboga, Kaplan Sefil, Nebihat, Özkan, Orhan Veli, Emel Nacar, Akküçük, Seçkin, Nacar, Emel, Ahmet Nacar, Okuyan, Hamza Malik, Seckin Akkucuk, Nacar, Ahmet, Hamza Malik Okuyan, Sedat Motor, Nebihat Kaplan Sefil   +15 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Comprehensive histological evaluation of bone implants [PDF]

, 2014
To investigate and assess bone regeneration in sheep in combination with new implant materials classical histological staining methods as well as immunohistochemistry may provide additional information to standard radiographs or computer tomography ...
Schneiders, Wolfgang, Rentsch, Claudia, Manthey, Suzanne, Rammelt, Stefan, Rentsch, Barbe   +4 more
core   +2 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Detection of fibrous astrocytes on histological sections of hippocampi using two different methods of silver impregnation [PDF]

Саратовский научно-медицинский журнал, 2017
Цель: выделение клеток волокнистой астроцитарной глии на гистологических срезах гиппокампов при использовании двух различных растворов солей серебра. Материал и методы. Гистологические срезы гиппокампов кроликов, разделенные на две группы, импрегнировали
Kazmin V.I., Datsenko A.V.
doaj  

Histological Methods to Assess Skeletal Muscle Degeneration and Regeneration in Duchenne Muscular Dystrophy. [PDF]

Int J Mol Sci, 2022
Dubuisson N, Versele R, Planchon C, Selvais CM, Noel L, Abou-Samra M, Davis-López de Carrizosa MA.   +6 more
europepmc   +1 more source